All Clinical & Diagnostics articles – Page 9
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News
Hospital awarded $12m to study best approach to treat mild pneumonia in young children
Ann & Robert H. Lurie Children’s Hospital of Chicago, in partnership with University of Utah Health, has been approved for $12 million in research funding for a study that will compare two ways to use antibiotics in young children with mild pneumonia.
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Largest study of its kind finds common lab tests aren’t reliable for diagnosing Long COVID
A new study found that most routine laboratory tests are not reliable for diagnosing Long Covid, also known as Post-Acute Sequelae of SARS-CoV-2 infection (PASC).
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Study reveals oleoyl-ACP-hydrolase underpins lethal respiratory viral disease
Respiratory infections can be severe, even deadly, in some individuals, but not in others. Scientists have gained new understanding of why this is the case by uncovering an early molecular driver that underpins fatal disease.
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Saliva indicates severity of recurrent respiratory infections in children
A saliva test can more accurately indicate the severity of recurrent respiratory infections in children than the standard blood test. If saliva contains too few broadly protective antibodies, a child is more likely to suffer from pneumonia episodes.
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Features
Mitigating the effects of temperature fluctuations on microbiological research
Temperature fluctuation is one of the most significant drivers of sample degradation. How can laboratories mitigate this issue to protect their irreplaceable specimens from being compromised or destroyed?
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Human clinical study launched using phage lysin to eliminate staph in the nasal microbiome
A “first-in-human” study with the novel drug candidate HY-133 began on 10 July with the recruitment of clinically healthy volunteers who tested positive for Staphylococcus aureus colonisation of the nose.
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Scientists uncover role of bacteria in keloid scarring
A new study explores the microbiome of keloids, which are treatment-resistant raised scars. Researchers found higher concentrations of bacteria and different types of bacteria than are found in normal skin, especially in deep layers of the keloid.
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Wearable health sensors are a powerful tool in disease detection
When seemingly healthy people receive an alert from a wearable sensor telling them they might have a respiratory virus, only a quarter of people follow up such an alert with an at-home viral test, according to a new study.
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Study finds how common skin bacterium causes chronic infections after orthopedic surgeries
Scientists investigating chronic bone infections have found that the common skin bacteria Cutibacterium acnes can persist as layers of biofilms for weeks on contaminated titanium or stainless-steel implants.
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New FAIRY rapid method determines virus infectivity
A new method that can rapidly determine whether a virus is infectious or non-infectious could revolutionise the response to future pandemics.
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Scientists identify possible new transmission factor in hospital-acquired Klebsiella infections
The dangerous multidrug resistant (MDR) pathogen, Klebsiella, thrives under nutrient-deprived polymicrobial community conditions found in hospital environments, a new study reveals.
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Surgical Infection Society issues new guidelines on the management of intra-abdominal infection
The Surgical Infection Society (SIS) has presented new evidence-based guidelines for the management of intra-abdominal infection (IAI) in the peer-reviewed journal Surgical Infections. “These guidelines are critical in the ongoing work by the Surgical Infection Society to decrease the number of deaths from the most common ...
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White paper explores innovative approaches to vaccine trials and pandemic preparedness
An international consortium of experts has created a white paper on innovative approaches for clinical vaccine research in order to be better prepared for future pandemics.
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Advanced nanofibrous membranes: tackling diabetic wounds with precision
Researchers have developed a poly (L-lactic acid) (PLLA) nanofibrous membrane enhanced with curcumin and silver nanoparticles (AgNPs), aimed at improving the healing of diabetic wounds.
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FedEx opens first European Life Science Center in Veldhoven
Federal Express Corporation, the world’s largest express transportation company, has opened its first European Life Science Center in Veldhoven, the Netherlands. The specialised cooling facility opens global access for the healthcare industry.
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‘Treat all’ strategy for patients with chronic hepatitis B virus infection
A new review explores the implications of a ’Treat-all’ strategy for chronic hepatitis B management following the 2022 Chinese guidelines which expanded treatment indications and simplified algorithms to enhance disease management.
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WHO prequalifies the first self-test for hepatitis C virus
The World Health Organization (WHO) has prequalified the first hepatitis C virus (HCV) self-test which can provide a critical support in expanding access to testing and diagnosis, accelerating global efforts to eliminate hepatitis C.
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AI able to identify drug-resistant typhoid-like infection from microscopy images in matter of hours
Artificial intelligence (AI) could be used to identify drug resistant infections, significantly reducing the time taken for a correct diagnosis, researchers have shown. An algorithm can be trained to identify drug-resistant bacteria correctly from microscopy images alone.
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Researchers develop noninvasive urine test for early detection of cervical cancer virus proteins
A new urine test can detect HPV16 E7 proteins, which are critical markers of cervical cancer risk, at extremely low levels, meaning women may be able to screen for cervical cancer without the discomfort and inconvenience of a traditional Pap test.
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New bio-based tool quickly detects concerning coronavirus variants
Researchers have developed a bioelectric device that can detect and classify new variants of coronavirus to identify those that are most harmful. It has the potential to do the same with other viruses, as well.