All Clinical & Diagnostics articles – Page 2
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News
Evaluating DNA impurities in recombinant adeno-associated virus
A new study indicates that DNA impurities derived from plasmid and host cell DNA are encapsulated into recombinant adeno-associated virus (rAAV) capsids as single-stranded DNA.
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Rapid and accurate diagnosis of urinary tract infections using targeted next-generation sequencing
A study shows that tNGS demonstrates advantages in rapid and accurate UTI diagnosis, particularly in detecting polymicrobial infections and analyzing antibiotic resistance genes. It shows promise as an effective complementary tool for UTI diagnostics.
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Bartonella and babesia found in brain tissue of child with seizures
In a new case study, researchers have found Bartonella henselae, Babesia odocoilei and Babesia divergens-like MO-1 DNA in brain tissue samples from a young child with seizures and suspected Rasmussen’s encephalitis.
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Researchers test new, more reliable method to detect chagas disease
Researchers have successfully tested a faster, more sensitive and reliable way to diagnose Chagas disease, a debilitating parasitic illness that affects approximately 6 million people worldwide.
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Bacteria invade brain after implanting medical devices
Researchers have discovered that bacteria can invade the brain after a medical device is implanted, contributing to inflammation and reducing the device’s long-term effectiveness.
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Immature platelet fraction offers clinical predictor for enhanced platelet recovery in patients with dengue fever
Immature platelet fraction (IPF) is recognized as a marker for thrombopoiesis, but a new study indicates that IPF% can be utilized as a predictor of platelet increase in patients with dengue infection.
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Helicobacter pylori treatment practices in the Asia-Pacific region
Researchers conducted an online survey of clinicians in the Asia-Pacific region to investigate treatment policies for H. pylori and confirmed that there is a growing consensus of the importance of primary and secondary prevention against H. pylori.
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COVID-19 pandemic worsened mother and infant birth outcomes
Mothers who became pregnant after the start of the pandemic, those who experienced moderate-to-severe infections during pregnancy, and those who had infections during the third trimester were more likely to have adverse outcomes.
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Symptoms of long-COVID can last up to two years after infection with COVID-19
According to a study of the COVICAT cohort, almost one in four people infected with SARS-CoV-2 suffered from long-COVID. In more than half of them the symptoms persisted for two years.
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Ultra-low dose CT aids pneumonia diagnosis in immunocompromised patients
Denoised ultra-low dose CT can effectively diagnose pneumonia in immunocompromised patients using only 2% of the radiation dose of standard CT, according to a study.
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Inhaled COVID vaccine study begins recruitment for phase-2 human trials
Researchers have started a phase-2 clinical trial on a next-generation, inhaled COVID-19 vaccine. Findings from the phase-1 trial indicate that the vaccine is more effective at inducing immune responses than traditional injected vaccines are.
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Scientists develop low-cost handheld sensor test for airborne bird flu
Researchers have developed a prototype sensor that detects a virus that causes bird flu (H5N1) in air samples. The low-cost handheld sensor detects the virus at levels below an infectious dose and could lead to rapid aerosol testing for airborne avian influenza.
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Features
Urinary tract infections: addressing the gender gap and advancing microbial insights
Urinary tract infections (UTIs) are among the most common bacterial infections worldwide, disproportionately affecting women and contributing to a significant healthcare burden.
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Insilico Medicine deploys the first bipedal humanoid AI scientist in fully-robotic drug discovery laboratory
Insilico Medicine, a clinical-stage biotechnology company pioneering generative AI for drug discovery and development, has announced the deployment of the first bipedal humanoid in its AI-powered fully-robotic drug discovery laboratory.
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Scientist who deployed glowing stars to detect disease named fellow of the Royal Society of Chemistry
The man who turned the science of glow-in-the-dark stars into ways to detect disease, Professor Richard Willson, has been elected as a fellow of the Royal Society of Chemistry.
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New biosensor can detect airborne bird flu in under 5 minutes
A new biosensor for monitoring aerosol particles of H5N1 works within five minutes, preserving the sample of the microbes for further analysis and providing a range of the pathogen concentration levels detected on a farm.
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A*STAR spin-off NalaGenetics implements nationwide drug reaction screening for leprosy patients in Indonesia
NalaGenetics, a spin-off from A*STAR Genome Institute of Singapore (A*STAR GIS), will be transforming leprosy treatments in Indonesia with a nationwide genetic screening programme with their PGx1301 diagnostic kit.
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Lung abnormalities seen in children and teens with long COVID
An advanced type of MRI uncovers significant lung abnormalities in children and adolescents with long COVID, according to a new study. PREFUL MRI doesn’t require the use of radiation or intravenous contrast agents and can be done while the patient breathes freely.
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New paper-based device boosts HIV test accuracy from dried blood samples
Scientists have trialled a more precise medical device to measure HIV viral loads by engineering a paper device with wax-printed patterns that create precise channels and collection spots, ensuring it consistently collects the same volume of blood.
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Paxlovid’s impact on hospitalization and death in COVID-vaccinated older adults far weaker than previously thought
A new study overturns the assumption that Paxlovid’s effectiveness in reducing COVID-19 hospitalizations and deaths in unvaccinated adults also applies to vaccinated adults.