All Clinical & Diagnostics articles – Page 2
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NewsComplexity key to preventing infection after heart surgery
Research indicates that uniform materials could be the culprit behind deadly infections that can occur when using synthetic materials for cardiovascular grafts.
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NewsCOVID-19 vaccination during pregnancy may help prevent preeclampsia
A new multinational study has found that COVID-19 vaccination during pregnancy, particularly when combined with a booster dose, significantly reduces the risk of preeclampsia, a serious and potentially life-threatening pregnancy complication.
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NewsNew antibody–drug conjugate strategy to block HIV infection
New antibody–drug conjugates (ADCs) combine a CD4 mimic with neutralizing antibodies for enhanced suppression of HIV infection. By targeting the gp120 on the viral envelope via a two-step mechanism, the ADCs effectively block viral entry.
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NewsNew clinical guidelines to reduce central line-associated bloodstream infection
Central line-associated bloodstream infections remain a major challenge in ICUs. A team of clinicians has proposed updated guidelines to standardize the clinical practices addressing CLABSI, aiming to reduce infection rates and improve outcomes for critically ill patients.
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NewsNew biosensor offers early warning system for disease
Researchers have developed a tissue-adhesive sensor for real-time oral health monitoring to combat long-term issues such as gum disease and tooth loss.
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NewsHPV cancer vaccine slows tumor growth, extends survival in preclinical model
Scientists discovered that systematically changing the orientation and placement of a single cancer-targeting peptide can lead to formulations that supercharge the immune system’s ability to attack HPV-driven tumors.
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NewsStiff gels slow germs: New study maps hydrogel properties that control bacterial growth
Scientists has found that firmer, lower water content hydrogels limit bacterial growth, with implications for designing antibacterial coatings, infection models, and advanced medical materials.
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NewsGenotype-specific response to 144-week entecavir therapy for HBeAg-positive chronic hepatitis B
HBV genotype B demonstrates superior histological responses to ETV therapy compared with genotype C, supporting the clinical value of HBV genotyping for personalized CHB management. These findings highlight the importance of considering viral genotype when evaluating treatment outcomes.
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NewsResearchers identify strategies for preventing the most infectious strains of S. aureus in the NICU
A new study has identified which strains of Staphylococcus aureus – commonly known as staph – are commonly transmitted in neonatal intensive care units and which specific strains are most likely to cause invasive and serious infections.
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NewsNew algorithm enhances microbiome biomarker discovery by integrating biological relationships
Researchers have developed a novel algorithm, Microbiome Elastic Feature Extraction (MEFE), that significantly improves the identification of microbiome biomarkers by incorporating phylogenetic, taxonomic, and functional relationships among microbes.
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NewsResearchers develop simple at-home tests for detecting cat and dog viruses
Researchers report improved lateral flow assays for at-home screening of cats and dogs. In tests on veterinary clinic samples, the assays demonstrated 100% sensitivity and reproducibility for both feline parvovirus and canine parvovirus.
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NewsCARB-X to support development of typhoid fever diagnostic from Chembio
CARB-X is awarding US$1.8 million to Chembio Diagnostic Systems, Inc. to develop a rapid point-of-care test for the detection of Immunoglobulin A (IgA) antibodies to diagnose acute infection of Salmonella enterica serovar Typhi.
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NewsTesting menstrual blood for HPV could be “robust alternative” to cervical screening
Testing menstrual blood for human papillomavirus (HPV) could be a “robust alternative or replacement” for current cervical cancer screening by a clinician, finds a study. The researchers say using menstrual blood for HPV testing is convenient and non-invasive.
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NewsBlood test may give insights into a person’s infection history
Which infections have you already come into contact with? In the future, a simple blood test may be all you need to answer that question. Researchers intend to investigate the sensors the immune system uses to identify pathogens.
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NewsBBSRC-backed spin-out launches rapid DNA air sequencing technology
New spin-out, Agnos Biosciences, has launched AirSeq, a rapid DNA air sequencing technology to transform pathogen detection across health, food and biosecurity. It brings to market a powerful new approach to detecting biological threats in the air.
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NewsWhy aren’t more older adults getting flu or COVID-19 shots?
This winter’s brutal flu season isn’t over, and COVID-19 cases have risen recently too. But a new poll taken in recent weeks shows that vaccination against both viruses lags among people 50 and over, and the US survey reveals key reasons why.
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NewsWHO calls for mental health to be central to neglected tropical disease care
A major new World Health Organization publication sets out, for the first time, a practical, evidence-based package of care to address the mental health impacts of neglected tropical diseases (NTDs) and the stigma that can prevent people from seeking care and participating fully in society.
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NewsPediatric investigation study reports significant shifts in post-COVID respiratory infection trends in children
To explore how the pandemic changed respiratory infection trends in children, researchers examined data from 73,096 pediatric patients hospitalized with acute respiratory tract infections in two coastal cities in eastern China with similar climates.
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NewsSepsis study IDs simple ways to save lives in Africa
Tuberculosis (TB) is a major unrecognized cause of deadly sepsis among people with HIV in Africa, a new study reveals. It found that more than half of the hundreds of patients enrolled in the study had TB and that immediate treatment increased their chances of survival significantly.
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NewsAddressing rapid viral evolution: research team unveils emerging techniques for RNA viruses diagnostics
The rapid evolutionary dynamics of RNA viruses, driven by high mutation rates and the consequent formation of complex quasispecies populations, present a formidable obstacle to conventional molecular diagnostic approaches, warn researchers.