All Clinical & Diagnostics articles – Page 10
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Survey finds many have misconceptions about sexually transmitted infection risk
Sexually transmitted infections (STIs) are on the rise in the U.S., including an 80% increase in syphilis over a five-year period, but a new survey finds many Americans have misconceptions on how STIs are spread and who should be treated.
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Think you might have COVID? Wait two days before you test, study suggests
researchers unveil a new mathematical model to quickly answer such questions, not only for COVID but also for emerging rapid tests for respiratory syncytial virus (RSV), the flu and other infectious diseases.
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3D-printed chip sensor detects foodborne pathogens for safer products
Researchers have developed a new method for detecting foodborne pathogens that is faster, cheaper, and more effective than existing methods.
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Scientists can now detect antibiotics in your fingerprints – aiding the fight against drug-resistant TB
A fingerprint may soon be all a doctor needs to check whether tuberculosis patients are taking their antibiotics – thanks to a new study. Scientists successfully detected the drugs in finger sweat – and with almost the same accuracy as a blood test.
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Simple test for flu could improve diagnosis and surveillance
A low-cost CRISPR-based paper strip test distinguishes between influenza types and can be reprogrammed to recognize different viruses including the H5N1 bird flu virus.
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Rapid test for UTI wins $10m Longitude Prize on AMR to transform fight against superbugs
Sysmex Astrego’s PA-100 AST System has won the $10m (£8m) Longitude Prize on AMR. The winning test provides accurate antibiotic susceptibility results in 45 minutes – compared to the 2-3 day wait patients currently face.
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Intranasal COVID-19 vaccine headed to clinical trials
CyanVac will sponsor a randomized, double-blind Phase 2b study to compare the efficacy and safety of CVXGA, its intranasal vaccine candidate designed to protect against COVID-19, against an FDA-approved mRNA-based COVID-19 vaccine.
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New rapid detection of bacteria in pediatric blood samples
Researchers have demonstrated that a new technology called u-dHRM (Universal Digital High-Resolution Melt) could quickly and accurately diagnose bloodstream infections.
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AI enables faster, more effective antibiotic treatment of sepsis
Sepsis is a life-threatening infection complication and accounts for 1.7 million hospitalizations and 350,000 deaths annually in the U.S. Fast and accurate diagnosis is critical, as mortality risk increases up to 8% every hour without effective treatment. Source: Ilanaer42 However, the current diagnostic standard is reliant on ...
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Living bioelectronics combine sensors and bacteria to heal skin
Researchers have created a unique prototype of a ‘living bioelectronic’ designed to treat psoriasis. The patch – a combination of advanced electronics, living cells and hydrogel – is showing efficacy in experiments in mice.
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New HIV reporter model: Visualizing HIV viral dynamics in cells with dual fluorescence
Researchers have developed a novel viral reporter system that allows for real-time visualization of HIV dynamics post-viral infection. HIV-Tocky features dual fluorescence to illuminate the process of provirus silencing and reactivation.
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Ingestible microbiome sampling pill technology takes a step forward
Significant progress has been made in the development of a small device, about the size of a vitamin pill, that can be swallowed and passed through the gastrointestinal tract to sample the full inventory of microorganisms.
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Precision medicine for sepsis in children within reach
Researchers used artificial intelligence to analyze a large set of clinical data and find a distinct group of patients who might respond better to targeted sepsis treatments.
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Oral nucleoside antiviral is progressing toward future pandemic preparedness
Oral obeldesivir has been shown to reduce disease severity in mice infected with one of several different coronaviruses, including SARS-CoV-2 (which causes COVID-19), SARS-CoV and MERS-CoV.
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Novel triple antibiotic combination offers breakthrough in combatting antibiotic resistance
A new study unveils a promising triple combination of antibiotics that significantly expands our arsenal against drug-resistant bacteria.
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Statisticians call for rigour and transparency in the evaluation of diagnostic tests
Recommendations designed to reframe the evaluation of in vitro diagnostic tests have been published - intended to help prevent future scenarios in which IVDs are marketed widely, but later attract serious concerns about the standards applied to their evaluation.
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Human cervix modeled in microfluidic organ chip helps target bacterial vaginosis
Engineered cervix with in vivo-like mucus production, hormone sensitivity, and associated microbiome creates novel testbed for bacterial vaginosis therapeutics and other treatments.
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New electrostatic sampler boosts indoor virus detection speed
Researchers have developed a groundbreaking electrostatic air sampler that enhances the rapid monitoring of airborne influenza and coronavirus.
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Living bioelectronic device monitors and manages psoriasis in mice
Coupling skin bacteria-laden hydrogel and electronics, researchers have introduced a bioelectronics system that can deliver management and adaptive treatment of skin inflammation. They test this approach in a mouse model of psoriasis.
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Lung microbiomes predict mortality in children following bone marrow transplant
Using a method that identifies all potentially pathogenic organisms present in the lungs, scientists have discovered links between certain microbial communities and the relative risk of mortality in children who undergo bone marrow transplants.