All CBASS articles
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NewsScientists reveal key bacterial immune mechanism
Researchers have uncovered a pivotal mechanism by which bacteria defend themselves against viral infection. Cyclic dinucleotides (CDNs), synthesized during activation of the cyclic oligonucleotide-based anti-phage signaling system (CBASS) immune mechanism, trigger the filamentous assembly of phospholipase effectors, which execute the downstream immune response.
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NewsFilament structure activates and regulates CRISPR-Cas ‘protein scissors’
Researchers have revealed the structure of the CRISPR-Cas ‘protein scissors’ found in bacteria and provided mechanistic details on how they function.
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NewsNew approach to tackling bacterial infections identified
Researchers unveil how the self-killing activity of bacteria can be harnessed in the fight against antibiotic resistance.
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NewsAntibiotics highjack bacterial immunity
Molecular defense system protects bacteria from viruses and at the same time makes them susceptible to antibiotics.
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NewsScientists uncover how bacteria recognize viral invasion and activate immune defenses
Researchers have discovered that bacteria sense phages via a defensive response called CBASS that detects viral RNA.