All candidalysin articles
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News
Candida albicans toxin plays a special role in the colonization of the digestive tract
Comparative studies on mice with a complete microbiome and a microbiome reduced by antibiotics now show that the previous assumption that the yeast form of Candida albicans is better suited for colonization needs to be revised.
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News
Insights into release of fungal toxin promise progress in treating infections
The toxin Candidalysin of the yeast Candida albicans is incorporated into an unusual protein structure during an infection, and researchers have now succeeded in deciphering the function of this unusual arrangement.
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News
Fungal infection in the brain produces changes like those seen in Alzheimer’s disease
Researchers have discovered how the fungus Candida albicans enters the brain, activates two separate mechanisms in brain cells that promote its clearance, and generates amyloid beta (Ab)-like peptides.
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News
Fungal toxin triggers NET traps formed by white blood cells
A new study sheds light on how neutrophils respond to C. albicans hyphae, which release a peptide toxin called candidalysin, exclusively secreted when C. albicans grows as hyphae and hence during invasive growth.