All Candida albicans articles
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Multi-disciplinary team awarded $3.9 million to study mixed fungal-bacterial infections
A multi-disciplinary team was recently awarded $3.9 million from the National Institute of Allergy and Infectious Diseases for a project aimed at unravelling intricate mysteries surrounding complex fungal-bacterial infections.
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Pandemic stranding ended up helping to solve mystery of synthetic polymers and fungi
A chemistry PhD student who was stranded during the pandemic used the time for research on Candida albicans, leading to a successful collaboration between natural product researchers and infection biologists from Germany and Australia.
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Vps21 signaling pathway regulates white-opaque switching and mating in Candida albicans
Researchers have discovered that the conserved Vps21 signaling pathway plays critical roles in the regulation of white-opaque switching and mating in Candida albicans, a major human fungal pathogen.
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Anti-inflammatory curbs spread of fungi causing serious blood infections
Researchers have discovered that a common anti-inflammatory drug, mesalamine, can replace the work of good bacteria in fighting the fungus Candida albicans in the gut.
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Cinnamon inspires intelligent nanodevice targeting bacteria and other pathogens
Researchers have developed an intelligent nano killer based on a component of cinnamon essential oil (cinnamaldehyde) for use as an antimicrobial agent.
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Mitochondrial phosphate carrier plays an important role in virulence of Candida albicans
Scientists have found that the lack of MIR1 gene, which encodes mitochondrial phosphate carrier, can lead to severe virulence defects in Candida albicans.
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Keto diet boosts lifesaving antifungal drug in mice
In animal tests, researchers have found that taking fluconazole in combination with a low-carb, high-fat keto diet worked significantly better at killing the fungus behind fungal meningitis than taking the medication alone.
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Scientists deploy synthetic amyloids to figure out ways of targeting biofilms
New research being presented at the Letters in Applied Microbiology ECS Research Symposium this May will reveal how scientists are investigating how macrophages can be used to break down amyloid plaques in biofilms.
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Maleimide derivative shows promise for treating clinical candidiasis
A new study demonstrates the efficacy of a novel maleimide analogue as a novel antifungal compound, highlighting its potential as a promising option for the treatment of clinical candidiasis.
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Candida albicans toxin plays a special role in the colonization of the digestive tract
Comparative studies on mice with a complete microbiome and a microbiome reduced by antibiotics now show that the previous assumption that the yeast form of Candida albicans is better suited for colonization needs to be revised.
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Insights into release of fungal toxin promise progress in treating infections
The toxin Candidalysin of the yeast Candida albicans is incorporated into an unusual protein structure during an infection, and researchers have now succeeded in deciphering the function of this unusual arrangement.
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Newly identified yeast could prevent fungal infections by outcompeting rivals, study suggests
Researchers have identified a yeast that could be used to prevent invasive candidiasis, a major cause of death in hospitalized and immunocompromised patients.
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Current standards for testing wound dressings don’t work for biofilms, study finds
Current standards for testing wound dressings do not work for biofilms, particularly in the case of polymicrobial biofilms, a new study has found. Testing of wound dressings is predominantly carried out on single species of microbes in isolation, even though the wound sterile environment is not sterile and is often ...
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Zinc shows promise as surprising emerging treatment for vaginal yeast infections
New research could one day pave the way for the treatment of vaginal yeast infections, by shedding new light on how microbes in the body absorb zinc.
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Visualizing fungal infections deep in living tissue reveals proline metabolism link to virulence
The first successful application of 2-photon intravital microscopy (IVM) to image the dynamics of fungal infections in the kidney of a living host reveals that Candida albicans requires the ability to metabolize proline to mount virulent infections.
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Drugs targeting iron regulation could be the answer to antifungal resistance
Drugs targeting iron uptake mechanisms could prove vital in the fight against human fungal pathogens, a new review suggests.
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Gut fungi trigger long-lasting severe COVID-19 immune response
Researchers have found that the growth of fungi in the intestinal tract, particularly strains of Candida albicans yeast, trigger an upsurge in immune cells whose actions can exacerbate lung damage.
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Fungal infection in the brain produces changes like those seen in Alzheimer’s disease
Researchers have discovered how the fungus Candida albicans enters the brain, activates two separate mechanisms in brain cells that promote its clearance, and generates amyloid beta (Ab)-like peptides.
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Fungal toxin triggers NET traps formed by white blood cells
A new study sheds light on how neutrophils respond to C. albicans hyphae, which release a peptide toxin called candidalysin, exclusively secreted when C. albicans grows as hyphae and hence during invasive growth.
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Gut hormone doubles as immune regulator for the fungal microbiome
Research shows that a gut hormone called peptide YY also plays a vital role in maintaining the health of the gut microbiome by preventing helpful fungi from turning into more dangerous, disease-causing forms.