All Cancer Microbiology articles – Page 8
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Gut microbiome changes linked to precancerous colon polyps
A new study has linked certain types of gut bacteria to the development of precancerous colon polyps.
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Engineered virus with immunotherapy safe and improves cancer outcomes
A new study validates the safety of a combination approach using an engineered virus and immunotherapy to target an aggressive brain cancer, and offers promise to adapt treatment strategies.
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Intestinal bacteria influence the growth of fungi
The bacteria present in the intestine provide information about the quantities of fungi of the potentially disease-causing Candida genus - among them, surprisingly, are lactic acid bacteria that are known for their protective effect against fungal infections.
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CRISPR-based drug candidate targets the microbiome
Scientists have engineered the first published CRISPR-based candidate for a drug - a combination of phages - that targets E. coli directly and leaves the microbiome intact.
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Tumour bacteria can trigger anticancer response
A novel approach to treating cancer uses bacteria that naturally reside within tumours to trigger a powerful anticancer immune response.
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Antibacterial treatment solves radiotherapy skin problem
A new study shows that a low-cost antibacterial regimen can prevent acute radiation dermatitis.
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Gene scissors used successfully in the laboratory against HIV-related virus
Researchers have provided initial proof of concept for a potential therapeutic approach targeting HTLV-1, a retrovirus that triggers aggressive forms of leukemia or an incurable spinal cord disease that leads to paralysis.
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Researchers find regulatory mechanism that keeps cancer-causing bacteria in check
Researchers have discovered an important mechanism that may have profound implications for how we prevent colorectal cancer.
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Engineered E. coli delivers therapeutic nanobodies to the gut
A genetically modified beneficial strain of bacteria blocks intestinal inflammation in a preclinical model of inflammatory bowel disease and has the potential to treat intestinal-based diseases.
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Proof of concept study uses bacteria to deliver radiation therapy to tumours
Researchers are using bacteria as an adapter to connect powerful radiation therapy to cancer cells.
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Study finds diverse differences in microbes in breast tumours from women of different races
The breast tumours of Asian, black and white women have very different cellular, microbial and genomic features that could potentially be used to personalize care or predict disease progression, according to new research by investigators at the Johns Hopkins Kimmel Cancer Center. Source: National Cancer Institute Potential ...
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Gut microbiome influences how lymphoma patients respond to CAR T therapy
Study finds antibiotic treatment and different types of microorganisms can impact chimeric antigen receptor T-cell therapy outcomes.
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Engineered bacteria track down tumours, then signal the immune cells
Researchers have created a ’bacterial suicide squad’ that targets tumours, attracting the host’s own immune cells to the cancer to destroy it.
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Boosting gut microbiota helps healing after colorectal cancer surgery
Researchers have shown for the first time in mice that modifying intestinal flora before surgery could reduce postoperative complications in colorectal cancer patients.
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Zika virus may combat prostate cancer - but study highlights possible side-effect
When researchers analyzed zika’s effects on normal and cancer cells, they discovered that while the virus can be used to treat the disease, it may trigger a harmful inflammatory process and damage the male reproductive system.
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Viruses that kill cancer cells show promise for triple-negative breast cancer when combined with chemo
Researchers have shared positive results from a phase 2 clinical trial of an oncolytic virus combined with standard chemotherapy in patients with early stage triple-negative breast cancer.
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Salmonella exposure poses a risk for colon cancer
Researchers who studied human colon cancer tissue samples and animal models have found that exposure to salmonella was linked with colon cancers that developed earlier and grew larger.
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Ovarian cancer linked to bacteria colonization in microbiome
A specific colonization of microbes in the reproductive tract is commonly found in women with ovarian cancer, according to a new study from Mayo Clinic’s Center for Individualized Medicine.
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Genetically engineered bacterium can synthesize melanin nanoparticles
Researchers have heterologously expressed a tyrosinase gene in Escherichia coli to synthesize melanin nanoparticles which offer potential for tumour treatment.
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Scientists synthesize precursors of powerful anti-cancer drug in yeast cells
Researchers have identified a novel method for the biological synthesis of catharanthine and vindoline - the two pharmacologic precursors of anti-cancer drug vinblastine - using yeast cells.