All Cancer Microbiology articles – Page 4
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NewsGut bacterium impairs liver cancer treatment, inducing immunotherapy resistance
Researchers discovered that transplanting the gut bacterium Phocaeicola vulgatus into mouse models of liver cancer induced immunotherapy resistance. The finding is consistent with clinical observations in patients, showing that patients with low levels of P. vulgatus responded better to treatment.
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NewsTraces of bacteria inside brain tumors may affect tumor behavior
Scientists have uncovered unexpected traces of bacteria within brain tumors. This discovery offers new insights into the environment in which brain tumors grow and sets the stage for future studies seeking to improve treatment outcomes.
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NewsNew bioelectroceutical platform triggers dual cell death, reverses immunosuppression in colorectal cancer
Scientists have developed a new “microbial fuel cell” platform that integrates electrogenic bacteria with piezoelectric nanoparticles to cooperatively eradicate colorectal tumors, reverse immunosuppression, and remodel the gut microbiome.
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NewsNew DNA analysis approach could transform understanding of disease evolution
By adapting techniques originally used to study ancient DNA from archaeological specimens, researchers were able to recover genetic information from nearly century-old medical samples.
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NewsScientists harness algae for a greener way to create functional gold nanoparticles
Researchers have pioneered a novel, sustainable method for synthesizing functionalized gold nanoparticles (AuNPs) using microalgae. This approach not only avoids the harsh chemicals used in conventional methods but also produces AuNPs that are more stable and less toxic to healthy cells.
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NewsSingle-cell insights reveal how HPV status reshapes penile tumor immunity
A study found that HPV-positive tumors in penile squamous cell carcinoma cases contained fewer proliferative macrophages and less exhausted CD8+ T cells, along with stronger chemokine signaling, revealing distinct immune remodeling associated with HPV infection.
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NewsHidden HPV-linked cell type may drive early cervical cancer, scientists report
A new study identifies tumor-promoting keratinocytes linked to HPV infection and poor prognosis. Scientists employed single-cell RNA sequencing (scRNA-seq) and multiplex immunohistochemistry (mIHC) to delineate the molecular landscape of early-stage CESC.
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NewsNew insights on gut microbes that prevent formation of cancer-causing compounds
Gut microbes metabolize dietary nitrates and nitrites and prevent the formation of cancer-causing compounds called nitrosamines. New research sheds light on these processes and pinpoints which types of bacteria are most important.
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NewsStudent’s unexpected rise as a researcher leads to critical new insights into HPV
In two years, a student went from lab novice to medical diagnostics honors student whose study revealed how mutations in HPV proteins may increase cancer risk.
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NewsGlobal Virus Network welcomes new centers of excellence across the Americas
The Global Virus Network (GVN), a coalition of leading medical virologists representing 80+ Centers of Excellence and Affiliates in 40+ countries, has announced the addition of three new Centers of Excellence.
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NewsEurope backs first cervical cancer vaccination campaign in Angola
Angola’s first national vaccination campaign will immunise over 2 million girls aged 9–12 against cervical cancer. The national rollout began this week with coordinated delivery across schools, clinics, and communities in all 21 provinces.
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NewsLighting up life: scientists develop glowing sensors to track cellular changes as they happen
Researchers have engineered living cells to use a 21st amino acid that illuminates protein changes in real time, providing a new method for observing changes within cells. The technique is effective in bacteria, human cells and live tumor models, making it possible to study complex diseases like cancer more ethically.
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NewsReview explores roles, mechanisms and applications of intra-tumoral microbiota in cancers
A recent review provides an overview of the hallmarks, roles, molecular mechanisms, and clinical applications of intra-tumoral microbiota in multiple human cancers.
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NewsNew platform for the production of versatile active ingredients
With the help of a newly developed chemo-enzymatic platform, researchers have succeeded in producing a large number of different furanolides in larger quantities and characterizing their biological activity.
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NewsStudy finds COVID-19 mRNA vaccine sparks immune response to fight cancer
Patients with advanced lung or skin cancer who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy drugs lived significantly longer than those who did not get the vaccine, researchers have found.
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NewsStudy reveals how bacteria in tumors drive treatment resistance in cancer
Researchers have uncovered a previously unknown way for microbes within tumors to contribute to treatment resistance in certain cancers. The study finds these microbes push cancer cells into a reversible resting state, allowing them to become resistant to certain chemotherapies.
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NewsSafer, more effective vaccines with new mRNA vaccine technology
A new messenger ribonucleic acid (mRNA) vaccine technology could make future vaccines safer, more effective, and less burdensome for patients. The new approach uses albumin-recruiting lipid nanoparticles to deliver mRNA precisely to lymph nodes while bypassing the liver.
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NewsScientists research potential anti-ulcer vaccine targeting Helicobacter pylori
Scientists are on the way to finding a vaccine to fight off the Helicobacter pylori bacterium, possibly preventing stomach ulcers and lowering the risk for stomach cancer. They used immunoinformatics to scan its genetic makeup and predict which parts can trigger a strong immune response.
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NewsEngineered bacterial therapy activates immune response in cancer preclinical studies
Researchers have developed a new bacterial immunotherapy that delivers immune-activating proteins directly to solid tumors, which can often suppress the immune system. ACTM-838 targets phagocytic immune cells within the tumor microenvironment.
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NewsChanges in gut microbiota influence which patients get AIG-related neuroendocrine tumors
Researchers have discovered how the balance of bacteria in the stomach affects the growth of neuroendocrine tumors (NETs). By identifying the specific bacteria involved and the biochemical reactions that cause tumor growth, they hope to detect which patients are most likely to develop cancer.