All Cancer Microbiology articles
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NewsHKU innovations achieve recognition at the 51st International Exhibition of Inventions at Geneva
The University of Hong Kong (HKU) secured 46 awards at the 51st International Exhibition of Inventions of Geneva, including recognition for a project aiming to gain immunity against the three major respiratory viruses through home-based toothbrushing.
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NewsTarget behind cancer drug shown to help fight influenza in mice
A protein already targeted by FDA-approved cancer drugs may also help the body fight influenza. A study found that Programmed Death-Ligand 1 (PD-L1), best known for helping tumors evade immune attack, instead helped immunocompromised mice clear flu-infected lung cells and survive infection.
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NewsNew drug candidate extremely effective against H. pylori bacterium
Researchers have discovered that metronidazole targets two central protective proteins of Helicobacter pylori: an enzyme responsible for detoxifying harmful reactive oxygen species and a protein that repairs damaged proteins.
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NewsScientists uncover how HPV-positive cancers hide from the immune system — and how to make them visible again
A new study solves a major mystery in cancer immunology by uncovering how HPV hides cancer cells from the immune system by using MARCHF8 to destroy MHC-I, which serves as a warning flag for the immune system.
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NewsEngineered bacteria deliver cancer drug directly inside tumors in mice
New research suggests that Escherichia coli Nissle 1917 (EcN) may be engineered with anticancer agents to treat cancerous tumors in mice. Researchers used EcN as a base for synthesizing Romidepsin (FK228), an FDA-approved drug with anti-tumor agents.
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NewsSevere COVID-19 and flu facilitate lung cancer months or years later, new research shows
Severe COVID-19 and influenza infections prime the lungs for cancer and can accelerate the disease’s development, but vaccination heads off those harmful effects, new research indicates.
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News‘Bugs delivering drugs’ – new approach to colorectal cancer treatment using common food-borne bacteria
Researchers have published a novel approach to fight colorectal cancer, using modified bacteria as a courier to deliver potent cancer-killing proteins into tumor cells.
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NewsStudy highlights gut–brain axis in pituitary tumor–related cognitive decline
Researchers conducted a prospective cross-sectional study to evaluate cognitive function in patients with pituitary neuroendocrine tumors and examine associations among tumor lineage, hormonal abnormalities, and gut microbiota composition.
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NewsGut microbes rewrite the rules of cancer immunotherapy
A review synthesizes growing evidence showing that commensal microbes enhance anti-tumor immunity by producing immune-active metabolites, remodeling the tumor microenvironment, and activating key immune cells such as dendritic cells and cytotoxic T cells.
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NewsChemically ‘stapled’ peptides used to target difficult-to-treat cancers
Researchers have developed a new technology that uses bacteria to build, chemically stabilise, and test millions of potential drug molecules inside living cells. The bacteria produce vast libraries of peptide molecules, and chemically stabilise them into defined shapes while they are being tested inside the cell.
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NewsCell-free DNA offers early warning for bloodstream infections in kids with leukemia
Researchers show that microbial cell-free DNA sequencing can predict bloodstream infections in children with leukemia days before the symptoms appear. Plasma microbial cell-free DNA sequencing (mcfDNA-Seq) offer a potential approach to protecting vulnerable patients by allowing treatment to start before the patient gets sick.
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NewsBiomarkers indicating higher liver cancer risk in chronic hepatitis B patients identified
Researchers have identified Hepatitis B RNA serum levels as a biomarker that more accurately stratifies risk of liver cancer in individuals who have been functionally cured of chronic hepatitis B.
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NewsHPV vaccination provides “sustained protection” against cervical cancer
Human papillomavirus (HPV) vaccination is associated with a significantly reduced risk of invasive cervical cancer, with no indication of waning protection up to 18 years after vaccination, finds a study.
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NewsResearchers engineer bacteria capable of consuming tumours from the inside out
A research team is developing a novel tool to treat cancer by engineering hungry bacteria to literally eat tumours from the inside out. They added a gene to the organism from a related bacterium that can better tolerate oxygen and found a way to activate the oxygen-resistant gene at just the right time.
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NewsNewly discovered virus linked to colorectal cancer
Researchers have discovered a previously undescribed virus in a common gut bacterium, Bacteroides fragilis. The virus appears more frequently in patients with colorectal cancer.
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NewsHow bacteria may promote breast cancer
Researchers have discovered how certain pathogenic bacteria in gut and breast tissue can promote breast cancer development and progression by hijacking a key metabolic enzyme known as spermine oxidase (SMOX).
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NewsScientists develop first-of-its-kind antibody to block Epstein Barr virus
Using mice with human antibody genes, scientists have developed new genetically human monoclonal antibodies that prevent two key antigens on the surface of the Epstein Barr virus (EBV) from binding to and entering human immune cells.
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NewsA yeast enzyme helps human cells overcome mitochondrial defects
An international team has experimentally uncoupled nucleotide synthesis from mitochondrial activity using ScURA, a yeast-derived genetic tool now available to the research community that will enable new explorations of cellular metabolism.
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NewsRhododendron-derived drugs now made by bacteria
Bioengineered E. coli bacteria can now produce a group of compounds with anticancer, anti-HIV, antidiabetic and anti-inflammatory activities. The compounds, orsellinic acid-derived meroterpenoids, are produced by Rhododendron species.
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NewsImmunity against common virus leveraged against pancreatic cancer
Researchers have discovered a promising new treatment approach for pancreatic cancer. The approach leverages the body’s natural immune response to cytomegalovirus (CMV), a common but typically harmless virus that most people are infected with at some point in their lives.