All Brigham and Women’s Hospital articles
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NewsResearchers identify signs tied to more severe cases of RSV
In a new study, researchers found an increase in NK cells in the airways of children with severe RSV as well as other alterations that suggest these cells may be contributing to disease severity.
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NewsStudy finds persistent infection could explain long COVID in some people
Researchers found people with wide-ranging long COVID symptoms were twice as likely to have SARS-CoV-2 proteins in their blood, compared to those without long COVID symptoms.
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NewsCan a drug-free nasal spray protect against deadly respiratory infections?
A novel nasal spray for preventing respiratory infections works by forming a protective coating on the nasal cavity, which captures airborne respiratory droplets and acts as a physical barrier against viruses and bacteria, while effectively neutralizing them.
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NewsStudy finds shingles increased risk of subsequent cognitive decline
A new study has found that an episode of shingles is associated with about a 20 per cent higher long-term risk of subjective cognitive decline, providing support for getting the shingles vaccine to decrease risk of developing shingles.
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NewsResearchers develop new way for beneficial microbes to survive extreme conditions and space exploration
The team’s formulations allow microbial therapeutics to maintain their potency and function over time despite extreme temperatures, harsh manufacturing processes, and radiation exposure.
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NewsStudy reveals a way to protect microbes from extreme conditions
By helping microbes withstand industrial processing, the method could make it easier to harness the benefits of microorganisms used as medicines and in agriculture.
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NewsStudy links gut microbiome changes to increased risk of type 2 diabetes
Researchers have found that specific species and strains of bacteria are linked to changes in the functioning of the gut microbiome and a person’s risk of type 2 diabetes.
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NewsRemoving gut bacteria’s potential ‘safe house’ may lower risk of colorectal cancer subtype
A new study has found an association between appendix removal and a decreased risk of colorectal cancer positive for tumor-promoting bacteria.
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NewsResearchers uncover genetic factors for severe Lassa fever
Researchers have found two key human genetic factors that could help explain why some people develop severe Lassa fever, and a set of LARGE1 variants linked to a reduced chance of getting Lassa fever.
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NewsAnti-HIV drugs may prevent complications from bacterial sepsis
A new study suggests that reverse transcriptase inhibitors — antiretroviral drugs also used to manage HIV infections — can be used to prevent inflammatory complications of bacterial sepsis.
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NewsB cell deficient patients gain protective T cell immunity after SARS-CoV-2 vaccination, infection
Researchers found that vaccinated B cell-deficient individuals had significantly reduced risk of moderate and severe disease in comparison to those who were not vaccinated, despite an absence of anti-spike antibody responses.
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NewsToothbrushing tied to lower rates of pneumonia among hospitalized patients
Researchers found that hospital-acquired pneumonia rates were lower among patients who received daily toothbrushing compared to those who did not.
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NewsStudy proposes new framework to identify keystone microbial species
Researchers have designed a new data-driven keystone species identification (DKI) framework that uses machine learning.
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NewsFourth dose of COVID vaccine boosts protection in patients with rheumatic disease
A new study suggests that the recommendation for patients receiving disease-modifying antirheumatic drugs to receive a fourth dose of the mRNA vaccine has saved lives and reduced hospitalizations among patients in this high-risk group.
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NewsStudy uncovers mediators of persistent HIV viremia
Researchers examining people with non-suppressible HIV viremia (NSV) despite receiving antiretroviral therapy (ART) have found large reservoirs of proviruses inserted into transcriptionally active regions of immune cell genomes.
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NewsOne in five patients experience rebound COVID after taking Paxlovid, new study finds
While Paxlovid remains a ‘life-saving drug,’ researchers found that patients experiencing virologic rebound after treatment may remain contagious.
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NewsBoston Children’s Hospital receives a contract of up to $9 million to improve flu vaccines
The Precision Vaccines Program (PVP) at Boston Children’s Hospital has been awarded a contract from NIAID to develop a small molecule adjuvant to enhance the effectiveness of flu vaccines.
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NewsResearchers discover associations among PTSD, diet, and the gut microbiome
A new study suggests that adhering to a Mediterranean diet may alleviate or prevent posttraumatic stress disorder (PTSD) symptoms.
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NewsEngineered probiotic developed to treat multiple sclerosis
Researchers are working on a new approach to target autoimmunity in the brain, leveraging designer bacteria to make treatment safer and more effective.
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NewsResearchers reveal why viruses like SARS-CoV-2 can reinfect hosts and evade immune response
Using a tool called VirScan, Brigham investigators found that people produced shared antibody responses to certain regions of the virus, likely leading to selective pressure and new variants that can repeatedly escape detection by prior immunity.
