All Bioengineering articles
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News
Application of heavy-ion irradiation mutagenesis to improve the production efficiency of the antifungal drug micafungin
Scientists have used heavy-ion irradiation to improve efforts to produce the semisynthetic echinocandin antifungal agent micafungin which derives from fungal natural product FR901379 produced by Coleophoma empetri.
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Scientists transform ubiquitous skin bacterium into a topical vaccine
Researchers have domesticated of a bacterial species that hangs out on the skin of close to everyone on Earth to create a vaccine that is a cream instead of needle.
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Nanorobot hand made of DNA grabs viruses for diagnostics and blocks cell entry
A tiny, four-fingered ‘hand’ folded from a single piece of DNA can pick up the virus that causes COVID-19 for highly sensitive rapid detection and can even block viral particles from entering cells to infect them.
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Building roots in glass, a bio-inspired approach to creating 3D microvascular networks using plants and fungi
Researchers have developed a new and convenient technique for building complex 3D microfluidic networks, using plants and fungi which grew their roots into a ‘soil’ medium of nanoparticles of glass (silica) and a cellulose based binding agent.
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Bioengineered yeast mass produces herbal medicine
Herbal medicine is difficult to produce on an industrial scale. A team of bioengineers have combatted this by manipulated the cellular machinery in a species of yeast so that one such molecule can now be produced in a fermenter at unprecedented concentrations.
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Bacterial protein discovered and engineered to better separate rare earth metals
A newly discovered protein naturally houses an unusual binding site that can differentiate between rare earth elements, and researchers have made it even better.
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Bioengineered mussel-inspired sticky microorganisms to help break down plastic waste
Scientists have tapped into nature’s adhesive genius, the sticky power of mussels, to create bioengineered microorganisms with powerful cling that could help transform environmental cleanup.
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New, modified CRISPR protein can fit inside virus used for gene therapy
Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells. Hongjian Wang and colleagues at Wuhan University, China, present these findings May 23rd in the ...
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Living bioelectronic device monitors and manages psoriasis in mice
Coupling skin bacteria-laden hydrogel and electronics, researchers have introduced a bioelectronics system that can deliver management and adaptive treatment of skin inflammation. They test this approach in a mouse model of psoriasis.
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Scientists harness plant viruses to deliver genome editing reagents in diverse plant species
The use of viral vectors to deliver genome editing components offers potential solutions to many current technical bottlenecks involved in genome editing in plants.
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Bioengineered enzyme creates natural vanillin from plants in one step
Researchers have developed an enzyme which can convert ferulic acid from plant waste into vanillin – the classic vanilla flavored compound.
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An adjuvant made in yeast could lower vaccine cost and boost availability
Scientists have wielded the power of synthetic biology to produce the active ingredient of soap bark, a molecule called QS-21, in yeast - a more environmentally friendly way to produce a key ingredient of vaccines.
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Innovative antiviral defense with new CRISPR tool
Scientists outline how they have overcome a significant obstacle that has hampered the effectiveness of Cas13d: its restriction to the nucleus of mammalian cells.
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From lab to grid: how living batteries could transform the energy landscape
As researchers find innovative ways to make these power sources more lightweight or longer-lasting, they must also ensure that their inventions are as sustainable as possible.
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Plastic-free vegan leather that dyes itself grown from bacteria
Researchers at Imperial College London have genetically engineered bacteria to grow animal- and plastic-free leather that dyes itself. In recent years, scientists and companies have started using microbes to grow sustainable textiles or to make dyes for industry – but this is the first time bacteria have been engineered to ...
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Study identifies protein responsible for gas vesicle clustering in bacteria
Scientists have presented the first identification of a protein that can regulate the honeycomb patterning of gas vesicles packed within microbes.
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New bioengineered protein design shows promise in fighting COVID-19
Researchers have designed a novel protein capable of binding to the spike proteins found on the surface of the coronavirus, allowing them identify and recognize the virus for diagnostic purposes, and to hinder its ability to infect human cells.
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Researchers open new leads in anti-HIV drug development, using a compound found in nature
Researchers have successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.
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3G microbial cell factories: achieving sustainable goals with engineered microorganisms
Scientists review the progress made in the development of artificial biological systems for 3G refineries over the last decade.
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Bacteria engineered to biosynthesize intricate protein complexes
Researchers have developed an innovative bioengineering approach using genetically modified bacteria that can incorporate protein cages around protein crystals, producing highly customized protein complexes.