All Bioengineering articles
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A novel approach to mapping and engineering enzymes for enhanced plastic recycling
Researchers have successfully engineered PETases, enzymes that are capable to depolymerize commercial plastic - polyethylene terephthalate (PET), through the innovative landscape profiling of enzymes’ genetic sequences and subsequently engineered them.
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A new vaccine approach could help combat future coronavirus pandemics
Researchers are able to create a mosaic nanoparticle vaccine - mosaic-8, based on the sarbecovirus receptor-binding proteins (RBDs), which would help combatting SARS-CoV-2 variants and other coronavirus subtypes.
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Novel nanoreactor CU@G - AMPs: A promising solution for antibacterial therapy
A novel sustainable antibacterial therapy - an antibiotic-free complex, Cu@G-AMPs, has been developed by a team of Chinese scientists to combat drug-resistant bacteria such as MRSA.
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Final synthetic yeast chromosome unlocks new era in biotechnology
A team of researchers has successfully synthesised the very first yeast chromosome using specialised genome-editing technique that provides insights for synthetic biology and biomanufacturing fields.
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Research using non-toxic bacteria to fight high-mortality cancers prepares for clinical trials
A promising research study in treating high mortality late-stage cancers with a non-toxic bacterial therapy - BacID - has proven to be safe and more targeted. The newly developed treatment would undergo clinical trials with cancer patients in 2027.
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Application of heavy-ion irradiation mutagenesis to improve the production efficiency of the antifungal drug micafungin
Scientists have used heavy-ion irradiation to improve efforts to produce the semisynthetic echinocandin antifungal agent micafungin which derives from fungal natural product FR901379 produced by Coleophoma empetri.
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Scientists transform ubiquitous skin bacterium into a topical vaccine
Researchers have domesticated of a bacterial species that hangs out on the skin of close to everyone on Earth to create a vaccine that is a cream instead of needle.
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Nanorobot hand made of DNA grabs viruses for diagnostics and blocks cell entry
A tiny, four-fingered ‘hand’ folded from a single piece of DNA can pick up the virus that causes COVID-19 for highly sensitive rapid detection and can even block viral particles from entering cells to infect them.
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Building roots in glass, a bio-inspired approach to creating 3D microvascular networks using plants and fungi
Researchers have developed a new and convenient technique for building complex 3D microfluidic networks, using plants and fungi which grew their roots into a ‘soil’ medium of nanoparticles of glass (silica) and a cellulose based binding agent.
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Bioengineered yeast mass produces herbal medicine
Herbal medicine is difficult to produce on an industrial scale. A team of bioengineers have combatted this by manipulated the cellular machinery in a species of yeast so that one such molecule can now be produced in a fermenter at unprecedented concentrations.
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Bacterial protein discovered and engineered to better separate rare earth metals
A newly discovered protein naturally houses an unusual binding site that can differentiate between rare earth elements, and researchers have made it even better.
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Bioengineered mussel-inspired sticky microorganisms to help break down plastic waste
Scientists have tapped into nature’s adhesive genius, the sticky power of mussels, to create bioengineered microorganisms with powerful cling that could help transform environmental cleanup.
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New, modified CRISPR protein can fit inside virus used for gene therapy
Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells. Hongjian Wang and colleagues at Wuhan University, China, present these findings May 23rd in the ...
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Living bioelectronic device monitors and manages psoriasis in mice
Coupling skin bacteria-laden hydrogel and electronics, researchers have introduced a bioelectronics system that can deliver management and adaptive treatment of skin inflammation. They test this approach in a mouse model of psoriasis.
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Scientists harness plant viruses to deliver genome editing reagents in diverse plant species
The use of viral vectors to deliver genome editing components offers potential solutions to many current technical bottlenecks involved in genome editing in plants.
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Bioengineered enzyme creates natural vanillin from plants in one step
Researchers have developed an enzyme which can convert ferulic acid from plant waste into vanillin – the classic vanilla flavored compound.
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An adjuvant made in yeast could lower vaccine cost and boost availability
Scientists have wielded the power of synthetic biology to produce the active ingredient of soap bark, a molecule called QS-21, in yeast - a more environmentally friendly way to produce a key ingredient of vaccines.
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Innovative antiviral defense with new CRISPR tool
Scientists outline how they have overcome a significant obstacle that has hampered the effectiveness of Cas13d: its restriction to the nucleus of mammalian cells.
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From lab to grid: how living batteries could transform the energy landscape
As researchers find innovative ways to make these power sources more lightweight or longer-lasting, they must also ensure that their inventions are as sustainable as possible.
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Plastic-free vegan leather that dyes itself grown from bacteria
Researchers at Imperial College London have genetically engineered bacteria to grow animal- and plastic-free leather that dyes itself. In recent years, scientists and companies have started using microbes to grow sustainable textiles or to make dyes for industry – but this is the first time bacteria have been engineered to ...