All Bioengineering articles
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Researchers reveal key mechanism behind bacterial cancer therapy
A research team has elucidated the mechanism behind bacterial cancer therapy using a genetically engineered bacterial strain.
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Designing self-destructing bacteria to make effective tuberculosis vaccines
Preclinical studies have demonstrated a more effective tuberculosis (TB) vaccine through engineering bacteria to self-destruct and swiftly stops the infection on cue, which activates a more robust immune response.
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Biosensing platform simultaneously detects vitamin C and SARS-CoV-2
A portable and sensitive biosensing device has been developed by engineering researchers to detect both SAR-CoV-2 and vitamin C simultaneously, to monitor and boost health for the general public.
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Researchers engineer biological reaction crucibles to rapidly produce proteins
Biomedical engineers have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, such as antibiotics.
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Scientists recode the genome for programmable synthetic proteins
Synthetic biologists were able to re-write the genetic code of an organism — a novel genomically recoded organism (GRO) with one stop codon — using a cellular platform that they developed enabling the production of new classes of synthetic proteins.
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Minecraft players can now explore whole cells and their contents - including yeast and bacteria
Scientists have translated nanoscale experimental and computational data into precise 3D representations of bacteria, yeast and human epithelial, breast and breast cancer cells in the video game Minecraft.
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Researchers discover new way to customize living materials for tissue engineering, drug delivery and 3D printing
Researchers have revealed novel sequence-structure-property relationships for customizing engineered living materials (ELMs), enabling more precise control over their structure and how they respond to deformation forces like stretching or compression.
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Fungal protein yields new ways to modulate cell activity remotely
A new study introduces tools that remotely and non-invasively communicate with and control the activity of engineered cells once they’ve entered the body. It focuses on a fungal protein the team have developed called Melt, which can be toggled by temperature.
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A novel approach to mapping and engineering enzymes for enhanced plastic recycling
Researchers have successfully engineered PETases, enzymes that are capable to depolymerize commercial plastic - polyethylene terephthalate (PET), through the innovative landscape profiling of enzymes’ genetic sequences and subsequently engineered them.
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A new vaccine approach could help combat future coronavirus pandemics
Researchers are able to create a mosaic nanoparticle vaccine - mosaic-8, based on the sarbecovirus receptor-binding proteins (RBDs), which would help combatting SARS-CoV-2 variants and other coronavirus subtypes.
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Novel nanoreactor CU@G - AMPs: A promising solution for antibacterial therapy
A novel sustainable antibacterial therapy - an antibiotic-free complex, Cu@G-AMPs, has been developed by a team of Chinese scientists to combat drug-resistant bacteria such as MRSA.
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Final synthetic yeast chromosome unlocks new era in biotechnology
A team of researchers has successfully synthesised the very first yeast chromosome using specialised genome-editing technique that provides insights for synthetic biology and biomanufacturing fields.
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Research using non-toxic bacteria to fight high-mortality cancers prepares for clinical trials
A promising research study in treating high mortality late-stage cancers with a non-toxic bacterial therapy - BacID - has proven to be safe and more targeted. The newly developed treatment would undergo clinical trials with cancer patients in 2027.
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Application of heavy-ion irradiation mutagenesis to improve the production efficiency of the antifungal drug micafungin
Scientists have used heavy-ion irradiation to improve efforts to produce the semisynthetic echinocandin antifungal agent micafungin which derives from fungal natural product FR901379 produced by Coleophoma empetri.
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Scientists transform ubiquitous skin bacterium into a topical vaccine
Researchers have domesticated of a bacterial species that hangs out on the skin of close to everyone on Earth to create a vaccine that is a cream instead of needle.
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Nanorobot hand made of DNA grabs viruses for diagnostics and blocks cell entry
A tiny, four-fingered ‘hand’ folded from a single piece of DNA can pick up the virus that causes COVID-19 for highly sensitive rapid detection and can even block viral particles from entering cells to infect them.
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Building roots in glass, a bio-inspired approach to creating 3D microvascular networks using plants and fungi
Researchers have developed a new and convenient technique for building complex 3D microfluidic networks, using plants and fungi which grew their roots into a ‘soil’ medium of nanoparticles of glass (silica) and a cellulose based binding agent.
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Bioengineered yeast mass produces herbal medicine
Herbal medicine is difficult to produce on an industrial scale. A team of bioengineers have combatted this by manipulated the cellular machinery in a species of yeast so that one such molecule can now be produced in a fermenter at unprecedented concentrations.
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Bacterial protein discovered and engineered to better separate rare earth metals
A newly discovered protein naturally houses an unusual binding site that can differentiate between rare earth elements, and researchers have made it even better.
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Bioengineered mussel-inspired sticky microorganisms to help break down plastic waste
Scientists have tapped into nature’s adhesive genius, the sticky power of mussels, to create bioengineered microorganisms with powerful cling that could help transform environmental cleanup.