All Bioengineering articles
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Microalgae and bacteria team up to convert CO2 into useful products
Most methods of genetically modifying the bacterium Escherichia coli and other microbes to convert carbon dioxide into useful biological products require additional carbon sources. A new study overcomes this limitation by combining the photosynthetic finesse of a single-celled algae with the production capabilities of the bacteria E. coli.
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Scientists devise comprehensive resource on microbial cell factories for sustainable chemical production
Scientists evaluated the production capabilities of various industrial microbial cell factories using in silico simulations and, based on these findings, identified the most suitable microbial strains for producing specific chemicals as well as optimal metabolic engineering strategies.
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Scientists unlock frogs’ antibacterial secrets to combat superbugs
Researchers exploited natural peptides derived from frogs and improved their structural designs as antibiotic candidates, which are effective against complex mock bacterial communities of drug-resistant pathogens in preclinical tests, sparing beneficial microbiota and human cells.
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Green recipe: Engineered yeast boosts D-lactic acid production
An optimal combination of genetic “recipe” in a yeast strain achieves high yields of D-lactic acid production from methanol, advancing eco-friendly and sustainable biomanufacturing.
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Rice research team creates universal RNA barcoding system for tracking gene transfer in bacteria
An interdisciplinary group of researchers at Rice University has developed an innovative RNA “barcoding” method to track gene transfer in microbial communities, providing new insights into how genes move across species.
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Magnetic microalgae on a mission to become robots
A team of researchers has developed a green algae-based biohybrid micro swimmer covered with magnetic material, whose swimming ability is largely unaffected by the coating.
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New CRISPR-based diagnostic test detects multidrug-resistant pathogens in blood without amplification
A highly sensitive amplification-free CRISPR-based diagnostic test is developed to rapidly detect pathogens, including multidrug-resistant bacteria, at low concentrations in blood samples.
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CeSPIACE: A broad-spectrum peptide inhibitor against variable SARS-CoV-2 spikes
CeSPIACE, a small remodified peptide, is able to block the binding of ACE2 receptor and the spike protein on SARS-CoV-2 and its variants. Hence, the cheap and simple peptide could treat COVID-19 infection and prevent reinfection after exposure of the virus.
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New CRISPRs expand upon the original’s abilities
By scouring through a massive bacterial metagenomic databases, researchers have discovered new CRISPR-Cas systems as efficient as the conventional one. One of the candidate system has found with the technological potential to expand its impact in research, biotechnology and medicine.
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Promising new research shows potential to cure recurrent urinary tract infectionsed
Researchers examine the effectiveness of nanogel as a drug delivery system to direct antibiotics into targeted infected cells to improve UTI treatment.
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New antibodies show potential to defeat all SARS-CoV-2 variants
Researchers discovered that a paired combination of antibodies binding to the two domains of the SARS-CoV-2 viral particle showed promising results in elimination of all virus variants caused in the COVID-19 pandemic.
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Researchers reveal key mechanism behind bacterial cancer therapy
A research team has elucidated the mechanism behind bacterial cancer therapy using a genetically engineered bacterial strain.
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Designing self-destructing bacteria to make effective tuberculosis vaccines
Preclinical studies have demonstrated a more effective tuberculosis (TB) vaccine through engineering bacteria to self-destruct and swiftly stops the infection on cue, which activates a more robust immune response.
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Biosensing platform simultaneously detects vitamin C and SARS-CoV-2
A portable and sensitive biosensing device has been developed by engineering researchers to detect both SAR-CoV-2 and vitamin C simultaneously, to monitor and boost health for the general public.
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Researchers engineer biological reaction crucibles to rapidly produce proteins
Biomedical engineers have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, such as antibiotics.
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Scientists recode the genome for programmable synthetic proteins
Synthetic biologists were able to re-write the genetic code of an organism — a novel genomically recoded organism (GRO) with one stop codon — using a cellular platform that they developed enabling the production of new classes of synthetic proteins.
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Minecraft players can now explore whole cells and their contents - including yeast and bacteria
Scientists have translated nanoscale experimental and computational data into precise 3D representations of bacteria, yeast and human epithelial, breast and breast cancer cells in the video game Minecraft.
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Researchers discover new way to customize living materials for tissue engineering, drug delivery and 3D printing
Researchers have revealed novel sequence-structure-property relationships for customizing engineered living materials (ELMs), enabling more precise control over their structure and how they respond to deformation forces like stretching or compression.
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Fungal protein yields new ways to modulate cell activity remotely
A new study introduces tools that remotely and non-invasively communicate with and control the activity of engineered cells once they’ve entered the body. It focuses on a fungal protein the team have developed called Melt, which can be toggled by temperature.
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A novel approach to mapping and engineering enzymes for enhanced plastic recycling
Researchers have successfully engineered PETases, enzymes that are capable to depolymerize commercial plastic - polyethylene terephthalate (PET), through the innovative landscape profiling of enzymes’ genetic sequences and subsequently engineered them.