All articles by Basil Fok – Page 6
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Sophisticated early warning system: How bacteria respond to threats
Recent research has found that exogenous petidoglycan fragments of Vibrio cholerae and other multidrug-resistant pathogens are able to trigger 3D biofilm formation as an universial danger response.
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Decoding HIV genomic tactics in viral replication
Research on HIV-1 unravels the viral and host translational regulations during viral replications through the identification of RNA structures and previously unrecognized genetic elements - this could bring potential therapeutic interventions to counter the viral manipulations.
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Antibiotic treatment for drug-resistant tuberculosis found to be safe and effective in clinical trial
Two clinical trials were conducted to successfully test an oral antibiotic levofloxacin for the preventive treatment of multidrug-resistant tuberculosis (MDR-TB).
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The hunt narrows for Ebola virus hosts
A cholesterol-trafficking receptor, Niemann-Pick C1 (NPC1), was identified for more efficient surveillance of host reservoirs of filoviruses, including Ebolaviruses. It narrows down the host species of the virus and links to the geographic information of pathogen emergence.
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Pediatric investigation study examines the diagnostic potential of microbial cell-free DNA testing
A research study has found that plasma-based microbial cell-free DNA testing served as a safer and faster alternative to conventional microbiological diagnostic tests for pediatric ear, nose and throat (ENT) infections.
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Bacterial small noncoding RNA promotes gut colonization by regulating sialic acid metabolism
A novel 3′ UTR-derived small noncoding RNA was discovered to regulate metabolism of N-acetylneuraminic acid in Salmonella enterica pathogenesis.
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Beach guardians: How hidden microbes protect coastal waters in a changing climate
Coastal water quality is closely impacted by the microbial compositions living in groundwater within beach sands due to the rising sea level, a new study reveals.
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New computer models open door to far more targeted antibiotics
A powerful computer-modelling approach has been developed to give the antibiotics a laser-like precision for targeting specific types of bacteria among specific parts of the human body.
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Hepatitis E vaccination is effective in an epidemic
A case-control study has proved the effectiveness of the two-doses Hecolin vaccine against a potential hepatitis E outbreak.
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How fungi strengthen their defenses - and how we could break through them
A research team has discovered that the enzyme Mod5 in the fungus Aspergillus fumigatus plays an important role in the modification of fungal tRNA and helps confer temporary antifungal resistance.
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Promising COVID-19 vaccine development in animal trials
Researchers developed a COVID-19 vaccine that deploys virus-like particles (VLPs) for immunity stimulation in mice.
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A new way to make microbial fuel cell - a 3D-printed fungal battery
Researchers have developed a full functional, non-toxic and biodegradable fungal battery, with enough to power a temperature sensor, which can be used in agriculture or in environmental research for several days.