All Aspergillus fumigatus articles
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NewsNew antimicrobials could help tackle deadly drug-resistant infections
Scientists have developed a promising new way to create safer and more effective treatments for life-threatening fungal infections. Using genome mining, they identified bacterial species capable of producing new, undiscovered antifungals.
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NewsTissue-resident immune cells defend human lungs from viral, bacterial, and fungal infections
A study shows that human lung tissue serves as a “reservoir” for a large number of tissue-resident memory T cells.. These cells stand ready to combat a surprising range of viruses, bacteria, and even deadly fungal pathogens.
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NewsScientists discover ‘hidden switch’ in immune cells that helps the body kill deadly fungus
Scientists have discovered a “control switch” inside our immune cells that helps the body destroy dangerous fungal infections. A protein called RAB5c helps white blood cells kill Aspergillus fumigatus – an airborne fungus that can cause life‑threatening lung infections in people with weakened immune systems.
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NewsGlobal strategy to combat drug‑resistant fungi is about to change
An increasing number of fungi are becoming resistant to medication, posing serious risks for patients with weakened immune systems. That is why fifty researchers from around the world are calling for action against drug‑resistant fungi.
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CareersSummer studentship: Owen investigates how fungal hyphae interact with lung cells
Owen Nicholson reports back on his AMI-sponsored summer studentship which investigated the role of Piezo1 in the immune response during fungal invasion of the human lung at the University of East Anglia.
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NewsHow an immune cell receptor dampens the fight against fungal infection
People are constantly exposed to fungal spores, including those of Aspergillus fumigatus, but individuals with weakened immune systems may develop life-threatening infections. In a recent study, researchers clarified the mechanisms by which the dendritic cell immunoreceptor (Dcir) suppresses neutrophil activity during infection with A. fumigatus.
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NewsThirty years of research shows increased resistance in fungi
Fungi are increasingly resistant to antifungals, and the variation in resistance has significantly increased, reveals an analysis of more than 12,000 lung samples collected over thirty years in Dutch hospitals.
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NewsWhen fungi take your breath: How a mold can unbalance the lungs
New study reveals that infection with Aspergillus fumigatus not only changes the lungs - the intestines and metabolism also play a surprising role.
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NewsHow fungi strengthen their defenses - and how we could break through them
A research team has discovered that the enzyme Mod5 in the fungus Aspergillus fumigatus plays an important role in the modification of fungal tRNA and helps confer temporary antifungal resistance.
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NewsDeadly mould strains highly likely to acquire resistance to new drugs
Scientists have identified strains of one of the world’s most dangerous fungal pathogens, already resistant to our most effective antifungal drugs, which are also five times more likely to acquire resistance to desperately needed new treatments in development. Source: Ufficio Comunicazione, Azienda Ospedaliera SS. Antonio e ...
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NewsHistoric outbreaks of coffee wilt disease linked to gene transfer from another fungus
The fungus that causes coffee wilt disease repeatedly took up segments of DNA from a related fungal pathogen, which contributed to successive outbreaks of the disease.
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NewsEnzyme produced by pathogenic fungus helps evade immune system and facilitates infection
Researchers found 62 proteins specific to spores of Aspergillus fumigatus, a fungal species that causes lung disease. The study showed that at least one of these proteins inhibits human human defense mechanisms.
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NewsResearchers discover key gene regulating virulence of fungus that causes severe lung infections
Scientists have found a potential target for novel therapeutic strategies to combat fungal infections caused by Aspergillus fumigatus and are now looking for a molecule that inactivates the protein expressed by the gene as a basis for a drug.
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NewsFungi elude antifungal treatments by restructuring cell walls
A new multi-institutional study has characterized how fungi adapt to restructure their cell walls, effectively thwarting current antifungal medications. This new information opens opportunities to devise more effective use of antifungal drugs.
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NewsMultidrug-resistant fungi found in commercial soil, compost and flower bulbs
A study has found high levels of multidrug-resistant fungi in commercially available compost, soil and flower bulbs. Named a critical public health threat by WHO, Aspergillus fumigatus is potentially deadly to immunocompromised people.
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NewsScientists unlock the secrets of disease-causing fungus Aspergillus fumigatus
A new study demonstrates the pivotal role of the Mitogen-Activated Protein kinase MpkA in both gliotoxin production and self-protection.
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NewsResearchers shed light on how one deadly pathogen makes its chemicals
Scientists have deciphered a previously unidentified cluster of genes responsible for producing sartorypyrones, a chemical made by the fungal pathogen Aspergillus fumigatus, whose family causes Aspergillosis in humans.
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NewsStatins team up with azoles to battle fungal infections
Researchers evaluated the antifungal efficacy of the pitavastatin-azole combination in silkworm models, suggesting its potential as an effective clinical treatment.
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NewsDrugs targeting iron regulation could be the answer to antifungal resistance
Drugs targeting iron uptake mechanisms could prove vital in the fight against human fungal pathogens, a new review suggests.
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NewsDeadly fungus beaten with treatment blocking fatty acid formation
Researchers have discovered a new way to attack fungal infections by blocking fungi from being able to make fatty acids, the major component of fats.