All Asia & Oceania articles – Page 27
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Researchers develop an efficient host-vector system for a model archaeon by solving CRISPR-based host-plasmid conflict
The replicase gene of pRN1, an archaeal cryotic plasmid, carries a DNA segment to be targeted by the host I‐A CRISPR system, and the CRISPR-based host-plasmid conflict is responsible for instability of pRN1‐derived vectors in the archaeon Saccharolobus islandicus REY15A.
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Scientists unveil crucial virulent milRNAs implicated in initial infection of Fusarium wilt
Researchers have unveiled crucial virulent miRNA-like small RNAs (milRNAs) implicated in the initial infection of F. oxysporum f. sp. cubense (Foc), the causal agent of devastating Fusarium wilt of banana (FWB).
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Scientists trace source and spread of HIV variant in Indonesia
A new study traces where the dominant HIV variant in Indonesia came from and how it spread from there, offering insights of possible value to the development of treatments against the disease.
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Indian ocean temperature anomalies predict global dengue trends
Sea surface temperature anomalies in the Indian Ocean predict the magnitude of global dengue epidemics, according to a new study - suggesting that the climate indicator could enhance the forecasting and planning for outbreak responses.
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Scientists probe spermidine production to combat emerging drug resistance in Salmonella
Scientists have pinpointed how Salmonella Typhimurium uses a key molecule called spermidine to shield itself from the onslaught of the host’s defence machinery - and an existing FDA-approved drug can reduce spermidine production.
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International Vaccine Institute, Baylor College of Medicine, and Regional Center for Innovation in Vaccines and Biopharmaceuticals AIP exchange an MOU
The International Vaccine Institute (IVI), an international organization with a mission to discover, develop, and deliver safe, effective, and affordable vaccines for global health, Baylor College of Medicine (Baylor), health science university and a Texas nonprofit corporation, and the Regional Center for Innovation in Vaccines and Biopharmaceuticals (CRIVB) AIP, a ...
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Astragalus polysaccharide enhances voriconazole metabolism under inflammatory conditions through the gut microbiota
Astragalus polysaccharide alleviates the reduction of VRC metabolism induced by LPS by inhibiting lipid accumulation and inflammatory cytokine levels in the serum and liver and improving the metabolic function of the liver, a new study shows.
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Decoding the complex genetic network of antimicrobial resistance in Campylobacter jejuni
A study focused on tetracycline resistance genes tetO and tetM - using phylogenetic tree analysis, it provided valuable insights into the genetic landscape and variants associated with C. jejuni.
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Gut bacteria metabolite shows promise for fighting inflammatory bowel disease
A new study highlights the molecular mechanisms underlying the anti-inflammatory effects of KetoC, a gut bacteria-generated linoleic acid metabolite, using mouse models.
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Tenofovir alafenamide treatment achieves positive results in Chinese chronic hepatitis B patients
A five-year treatment regime with tenofovir alafenamide achieves high rates of viral suppression, alanine aminotransferase normalization, and favorable bone and renal safety in Chinese chronic hepatitis B patients.
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Study identifies immunity threshold for protection against COVID-19 in children
Researchers have found rather than antibodies, other arms of the immune system – T cells and memory B cells – provide durable protection against symptomatic SARS-CoV-2 infection in children.
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Orangutan treats wound with antimicrobial, pain-relieving plant
A Sumatran orangutan with a facial wound ate and repeatedly applied sap from a plant with anti-inflammatory and pain-relieving properties commonly used in traditional medicine. He also covered the entire wound with the green plant mesh.
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Study reveals worrying links between bacteremia and probiotic use
Researchers using whole-genome sequencing found that all identified Clostridium butyricum bacteremia strains were probiotic derivatives.
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Researchers discover key functions of therapeutically promising jumbo viruses
Identifying core replication processes has moved scientists closer to tapping phage as a treatment in the growing antibiotic resistance crisis.
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Marriage of synthetic biology and 3D printing produces programmable living materials
Researchers have 3D printed a bioink containing plant cells that were then genetically modified, producing programmable materials. Applications could someday include biomanufacturing and sustainable construction.
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Scientists uncover how Parkinson’s disease symptoms may be exarcerbated by COVID-19 infection
A new study provides insights into specific genes that may serve as biomarkers for Parkinson’s Disease and highlights the potential interaction between PD and COVID-19.
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Scientists reveal interaction mechanism between intestinal microbial environment and tumor immune microenvironment
Scientists have unveiled the mechanism of tumor immune evasion mediated by the microorganism C. scindens in colorectal cancer. Additionally, they developed a phage-based intervention method.
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Rapid nanoplasmonic-enhanced detection of SARS-CoV-2 and variants on DNA aptamer metasurfaces
The rapid nanoplasmonic-enhanced detection enabled by DNA aptamer metasurfaces holds promise for efficient screening of SARS-CoV-2 and its variants in clinical settings, airports, and other high-traffic areas.
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Phytopathology Research Forum highlights advances in plant pathology research in China
The event aims to facilitate discussions about cutting-edge developments in plant pathology research, phytopathology research innovations, and domestic and foreign academic exchanges.
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Scientists ID transcripts involved in antibiotic resistance mechanism of two critical superbugs
A new study uncovers a drug resistance gene’s divergent evolution, which could open new vistas for MDR prognosis and can be informative in antimicrobial therapeutics research.