All Antimicrobials articles – Page 4
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News
Marine natural product derivative offers new therapeutic strategy to inhibit enterovirus A71 replication
Researchers revealed that the inhibition of enterovirus A71 (EV-A71) replication can be achieved by targeting the human coatomer subunit zeta-1 (COPZ1) using a marine natural product derivative known as MPA-CF3.
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SKAN Research Trust and Quadram Institute Bioscience to develop novel microbial therapies
SKAN Research Trust and Quadram Institute Bioscience will apply the TraDIS-Xpress platform to study the action of traditional medical compounds on bacteria, aiding in the reformulation and development of novel antibacterial regimens.
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WHO releases report on state of development of antibacterials
Although the number of antibacterial agents in the clinical pipeline increased from 80 in 2021 to 97 in 2023, there is a pressing need for innovative agents for serious infections and to replace those becoming ineffective due to widespread use, the WHO says.
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Wooden surfaces may have natural antiviral properties - and the species matters
Wood has natural antiviral properties that can reduce the time viruses persist on its surface — and some species of wood are more effective than others at reducing infectivity.
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Innovative phage lysin HY-133 enters phase I clinical study
HYpharm’s innovative preventive agent HY-133 has reached the first clinical trial phase. HY-133 is specifically effective against Staphylococcus aureus including multi-resistant strains and is intended to combat its colonisation in the nose.
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Uncovering the potential of ‘golden flower’ and its fermentation application in tea
A new review examines the biological characteristics and fermentation applications of Eurotium cristatum, commonly known as the ’golden flower’, a dominant microbial strain in the fermentation process of Fu brick tea.
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Water-soluble version of bacterial enzyme may help researchers develop new antibiotics
Researchers created a water-soluble version of an important bacterial enzyme, which can now be used in drug screens to identify new antibiotics.
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Novel lipopeptide produced by bacterium proves lethal against Staphylococcus aureus
A novel antibacterial lipopeptide produced by the bacterium Serratia marcescens has been shown to be highly effective in killing Staphylococcus aureus – one of the most important pathogens occurring in humans.
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World famous Roman Baths could help scientists counter antibiotic resistance
The world-famous Roman Baths are home to a diverse range of microorganisms which could be critical in the global fight against antimicrobial resistance, a new study suggests.
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Newly isolated antibodies may aid effort to fight influenza B
Researchers have isolated human monoclonal antibodies against influenza B, a significant public health threat that disproportionately affects children, the elderly and other immunocompromised individuals.
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The world’s most powerful anti-fungal chemistries cause fungal pathogens to self-destruct
Scientists have discovered that the most widely-used class of antifungals in the world cause pathogens to self-destruct. The research could help improve ways to protect food security and human lives.
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Antibacterial protein offers new therapeutic target against pancreatic cancer
A recent study describes how pancreatic cancer stem cells take advantage of an antibacterial protein, PGLYRP1, to evade the immune system and protect themselves from early elimination.
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The effect of combinations of antibiotics and natural products on antimicrobial resistance
Thymol, rosemary oil, curcumin, capsicum, and moringa seed extract showed the highest synergistic activity with tested antibiotics against two key pathogens, a new study shows.
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Cinnamon inspires intelligent nanodevice targeting bacteria and other pathogens
Researchers have developed an intelligent nano killer based on a component of cinnamon essential oil (cinnamaldehyde) for use as an antimicrobial agent.
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Probiotic bacteria from fermented grain byproduct can battle E coli invasion in mouse gut
Probiotic bacteria isolated from corn steep liquor - a by-product of fermented maize - can prevent E coli invasion in the mouse gut, reveals new research presented at the recent Letters in Applied Microbiology ECS Research Symposium.
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'Failed drug' could offer new approach to Epstein-Barr virus and resulting diseases
Researchers have found that the Epstein-Barr virus triggers infected cells to ramp up the production of an enzyme known as IDO1, a discovery that offers a promising starting point for putting the brakes on EBV.
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Mitochondrial phosphate carrier plays an important role in virulence of Candida albicans
Scientists have found that the lack of MIR1 gene, which encodes mitochondrial phosphate carrier, can lead to severe virulence defects in Candida albicans.
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Matcha mouthwash inhibits bacteria that causes periodontitis
Matcha, a finely ground green tea powder, may help inhibit the growth of Porphyromonas gingivalis, one of the chief bacterial culprits behind periodontitis.
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AI reveals critical gaps in global Antimicrobial Resistance research
Researchers developed global maps showcasing regional, methodological, and sectoral AMR research activities, confirming a lack of interdisciplinary collaboration, particularly in low-income countries, where the burden of increasing AMR is most acute.
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Features
Unlocking the therapeutic potential of herbal teas
Delve into the diverse array of bioactive compounds and uncover a mosaic of health-enhancing properties.