All Antimicrobials articles
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NewsScientists unlock frogs’ antibacterial secrets to combat superbugs
Researchers exploited natural peptides derived from frogs and improved their structural designs as antibiotic candidates, which are effective against complex mock bacterial communities of drug-resistant pathogens in preclinical tests, sparing beneficial microbiota and human cells.
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NewsResearchers achieve de novo biosynthesis of plant lignans using synthetic yeast consortia
Researchers have achieved the biosynthesis of the antiviral ingredient lignan glycoside in yeast Saccharomyces cerevisiae. By mimicking the spatial and temporal regulation of plant biosynthesis, they designed a system with obligated mutualism, enabling metabolic division of labor among different yeast strains.
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NewsSelective G6PDH inactivation for Helicobacter pylori eradication with transformed polysulfide
A new study highlights a novel mechanism of action driven by polysulfides, presenting a promising alternative strategy for combating H. pylori infections.
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NewsNature’s warriors: How rice plants detect and defend against viral invaders
A groundbreaking study uncovers a molecular mechanism by which rice cells perceive viral infections and initiate antiviral response, which significantly contributes to understanding of virus-host interactions for further disease resistance breeding.
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NewsJapanese plant Daphne pseudomezereum yields anti-HIV daphnane diterpenoids
Scientists have discovered for the first time that Daphne pseudomezereum (commonly known as Onishibari) contains a substance inhibiting replication of human immunodeficiency virus (HIV).
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NewsCurrent antivirals likely less effective against severe infection caused by bird flu virus in cows’ milk
Scientists found that in a preclinical model, two FDA–approved flu antivirals generally did not successfully treat severe H5N1 infections. Meanwhile, the route of infection, whether through the eye, the nose or the mouth, significantly impacts effectiveness.
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NewsPromising new research shows potential to cure recurrent urinary tract infectionsed
Researchers examine the effectiveness of nanogel as a drug delivery system to direct antibiotics into targeted infected cells to improve UTI treatment.
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NewsClove oil yields new Pickering emulsion formulation with enhanced antibacterial properties
Researchers developed a sustainable Pickering emulsion using carbon quantum dots (CQDs), promising solid particles for food applications, derived from clove essential oil residue. They found that CQDs with 40% ethanol demonstrated the highest emulsifying efficacy.
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NewsA 'Trojan Horse' approach to develop new antimalarial drugs
Researchers have discovered a key process whereby malarial parasites take up a human blood cell enzyme, which could provide a new approach for antimalarial treatment.
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NewsCentauri Therapeutics selects first clinical candidate for immunotherapeutic treatment of Gram-negative bacterial infections
Centauri Therapeutics Limited has announced the selection of its first clinical candidate in the ABX-01 programme. The compound is designed to target serious Gram-negative bacterial infections in the lung.
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NewsUltrasound cleaning promotes phenolic synthesis in fresh-cut red cabbages
Not only can ultrasonic cleaning technology enhance the quality of fruits and vegetables and reduce microbial contamination on their surfaces but it can also serve as an abiotic stressor, inducing the synthesis and accumulation of bioactive compounds.
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NewsNew modeling approach could help design antivirals for shape-shifting viruses
New research utilizes an innovative computational modeling approach to capture the complex and diverse shapes that viral proteins can adopt.
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NewsRising threat of carbapenem-resistant Enterobacteriales (CRE) spurs urgent healthcare alert
The deteriorating epidemiological situation of carbapenem-resistant Enterobacteriales (CRE) has spurred ECDC to alert EU/EAA countries to the importance of controlling the spread of CRE infections to safeguard their healthcare systems.
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CareersSummer studentship: Ojewale finds novel Actinomycetes offer rare antimicrobial metabolites
Ojewale Ifeoluwa Florence reports back on her AMI-sponsored summer studentship which focused on the investigation of Actinobacteria found in local freshwater environments in Ogun State, Nigeria, under supervisor Dr. Amina Badmos.
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NewsDelicate nanoflower is deadly to bacteria
A carnation-like nanostructure could someday be used in bandages to promote wound healing. Researchers report that laboratory tests of their nanoflower-coated dressings demonstrate antibiotic, anti-inflammatory and biocompatible properties.
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NewsNovel nanoreactor CU@G - AMPs: A promising solution for antibacterial therapy
A novel sustainable antibacterial therapy - an antibiotic-free complex, Cu@G-AMPs, has been developed by a team of Chinese scientists to combat drug-resistant bacteria such as MRSA.
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NewsViruses and the human cell: The evolutionary arms race
Researchers have discovered a unique genetic mechanism that provides cells with rapid and efficient protection against viruses. The findings could lead to the development of new therapeutics.
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NewsTowards improved pandemic preparedness: Launch of new EU project COMBINE
A project for the targeted development of antiviral therapies for newly emerging viruses, COMBINE focuses on the critical virus-cell binding step, aiming to identify key factors and potential therapeutic targets involved early in viral infections.
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NewsBird flu is mutating - but antivirals still work
Researchers have identified nine mutations in a bird flu strain from a person in Texas. The bad news: this strain is more capable of causing disease and replicates better in the brain. Good news: approved antivirals are still effective.
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NewsHow fungi strengthen their defenses - and how we could break through them
A research team has discovered that the enzyme Mod5 in the fungus Aspergillus fumigatus plays an important role in the modification of fungal tRNA and helps confer temporary antifungal resistance.