All Antimicrobial Resistance articles – Page 3
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News
E. coli variant may cause antimicrobial resistance in dogs and humans
Researchers studying antimicrobial-resistant E. coli – the leading cause of human death due to antimicrobial resistance worldwide – have identified a mechanism in dogs that may render multiple antibiotic classes ineffective.
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Discharge of untreated hospital effluent is a key driver of multidrug resistance, study finds
A new study has highlighted the discharge of untreated hospital effluent to the environment as a major driver of multidrug resistance among the microbial community.
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AI able to identify drug-resistant typhoid-like infection from microscopy images in matter of hours
Artificial intelligence (AI) could be used to identify drug resistant infections, significantly reducing the time taken for a correct diagnosis, researchers have shown. An algorithm can be trained to identify drug-resistant bacteria correctly from microscopy images alone.
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Scientists discover how to improve vaccine responses to potentially deadly bacterium
Researchers have shown in an animal model that targeting a key suppressive immune molecule (IL-10) during the delivery of a vaccine improves the ability of the vaccine to protect against infection.
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News
Western superbugs do not dominate in Pakistan, study reveals
Certain antibiotic-resistant strains of bacteria endemic to the UK, Norway and the USA have not taken hold in Pakistan despite the widespread use of antibiotics in this region.
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Careers
Connecting with microbiologists and presenting research: Oluwole Owoyemi reports back from ASM 2024
Medical microbiologist Oluwole Owoyemi of Achievers University Owo and Federal University of Technology, Akure, reports back from ASM MICROBE 2024 after being awarded a Scientific Event Travel Grant by Applied Microbiology International.
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Mobile phone data helps track pathogen spread and evolution of superbugs
Combining genomic data and human travel patterns over a 14-year period in South Africa reveals key insights into the spread, evolution and resistance patterns of a major bacterium behind pneumonia and meningitis globally.
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News
Treatment with a mixture of antimicrobial peptides can impede antibiotic resistance
A common infection-causing bacteria was much less likely to evolve antibiotic resistance when treated with a mixture of antimicrobial peptides rather than a single peptide, making these mixtures a viable strategy for new antibiotic treatments.
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Coumarin glycosides reverse enterococci-facilitated enteric infections
Researchers have developed a dietary therapeutic for enterococci-mediated infections.
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Researchers thwart resistant bacteria’s strategy
Researchers have discovered a weakness in Pseudomonas aeruginosa with the potential to become the target for a new way to attack it.
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Degradation of cell wall key in the spread of resistance
A new study shows how an enzyme breaks down the bacteria’s protective outer layer, the cell wall, and thus facilitates the transfer of genes for resistance to antibiotics.
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AI helps mine genetic elements from ancient genomes to tackle antibiotic resistance
Scientists have developed an artificial intelligence tool to mine the vast and largely unexplored biological data—more than 10 million molecules of both modern and extinct organisms— to discover new candidates for antibiotics.
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Features
Infection, immunity and the One Health response in Indonesia
Infectious diseases (IDs) are a major health issue in Indonesia, as in many tropical low- and middle-income countries (LMICs), placing a significant economic burden on limited resources. Vaccination may have a critical role to play in the prevention of zoonotic infectious diseases.
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News
Diagnostic stewardship approach to C. diff reduces unnecessary testing
Revised rules for when Clostridioides difficile tests could be ordered helped to reduce inappropriate testing by 20%, which in turn can help rein in the overtreatment of patients.
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E. coli sends out SOS when antibiotics attack, sparking emergency mode
Antibiotics damage E. coli DNA, including by causing formation of single strands of incomplete DNA inside the cell. When that happens, it’s like lighting a match under a smoke detector, according to a new study.
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News
Rapid test for UTI wins $10m Longitude Prize on AMR to transform fight against superbugs
Sysmex Astrego’s PA-100 AST System has won the $10m (£8m) Longitude Prize on AMR. The winning test provides accurate antibiotic susceptibility results in 45 minutes – compared to the 2-3 day wait patients currently face.
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WHO releases report on state of development of antibacterials
Although the number of antibacterial agents in the clinical pipeline increased from 80 in 2021 to 97 in 2023, there is a pressing need for innovative agents for serious infections and to replace those becoming ineffective due to widespread use, the WHO says.
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Researchers discover how a deadly strain of salmonella fine-tunes its infection tactics
A new study investigates how pathogens like salmonella change their disease characteristics under fluid shear conditions like those they encounter in our bodies during infection.
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News
Temperature could be the new weapon in the battle against antibiotic resistance
Scientists have found that a small increase in temperature from 37 to 40 degrees Celsius drastically changes the mutation frequency in E. coli bacteria, which facilitates the development of resistance.
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News
Berberine could treat eczema-exacerbated staph infections
Eczema, a skin inflammatory disease that causes dry, itchy and inflamed skin, affects millions worldwide. Eczema is associated with an altered skin microbiome and higher colonization by Staphylococcus aureus. Source: NIAID/NIH Scanning electron micrograph of methicillin-resistant Staphylococcus aureus(MRSA, brown) surrounded by cellular debris. A new study, ...