All Antimicrobial Resistance articles – Page 21
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Newborns worldwide dying from sepsis as antibiotics lose their bite
A global observational study involving more than 3,200 newborn babies suffering from sepsis in 11 countries has shown that many newborns are dying because the antibiotics used to treat sepsis are losing their effectiveness.
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Novel combination therapy counters antibiotic-resistant Mycobacterium infections
Researchers have discovered a novel therapy by combining two antibiotics, rifaximin and clarithromycin, to treat Mycobacterium abscessus, a non-tuberculous mycobacterium (NTM) that causes chronic lung-related infections.
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Global response to antimicrobial resistance ‘insufficient’
Governments around the world must do more to tackle the growing threat of drug-resistant infections, new research suggests.
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Previously unknown antibiotic resistance widespread among bacteria
A new study shows that bacteria in almost all environments carry resistance genes, with a risk of them spreading and aggravating the problem of bacterial infections that are untreatable with antibiotics.
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Drugs pipeline rife with strategies to combat MRSA
A host of new antimicrobial strategies are in the development pipeline that could provide hope for healthcare sectors battling multi-drug resistant Staphylococcus aureus infections.
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Study uncovers how Leishmania parasite adapts so quickly to drugs
Scientists probing the parasite’s gene expression regulation during mRNA translation have discovered how it is able to preemptively and quickly adapt and respond to drug treatments.
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Staph mechanism for resistance to last resort drug is uncovered
New research has revealed the mechanism of transcriptional regulation via S-nitrosylation for resistance to last resort drug vancomycin in Staphylococcus aureus.
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AI-found drug may combat drug-resistant infections
Scietntists used a machine-learning algorithm to identify a compound that kills Acinetobacter baumannii, a bacterium that lurks in many hospital settings.
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AI deployed to find promising antibiotic to fight evasive hospital superbug
Scientists have used artificial intelligence to discover a new antibiotic which could be used to fight a deadly, drug-resistant pathogen that strikes vulnerable hospital patients.
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Microplastics changing gut microbiomes of wild seabirds
An international team of scientists has found evidence that microplastics in the digestive tract of seabirds altered the microbiome of the gut – increasing the presence of pathogens and antibiotic-resistant microbes, while decreasing the beneficial bacteria found in the intestines.
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Anti-microbial nanonets ease inflammation during sepsis
Pharmaceutical scientists have developed multi-functional synthetic peptide nanonets for relieving inflammation caused by bacterial infection. This is achieved by concurrent trapping of bacterial endotoxins and pro-inflammatory cytokines.
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Unusual cellular metabolism in fungi linked to AMR
Scientists have discovered that aberrant cellular metabolism in Candida fungi is linked to drug resistance, potentially opening up new possible pathways to antimetabolite therapies.
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Neglected 80yo antibiotic tackles AMR bacteria
An old antibiotic may provide much-needed protection against multi-drug resistant bacterial infections, according to a new study.
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Peptide combats multidrug-resistant bacteria in less than one hour
A synthetic peptide inspired by molecules secreted by the probiotic bacterium Lactobacillus plantarum has presented promising antibacterial results within one hour in laboratory trials.
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Tracking AMR in E. coli isolated from swine reveals worrying trends
Scientists have carried out the first surveillance study in the US that looks at antimicrobial resistance in E. coli from swine at slaughter.
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Resistant Candida auris on rise in Germany, setting off alarm signals
The number of cases of Candida auris has increased in Germany in recent years, adding to outbreaks worldwide, a new study has revealed.
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Bacteria evolve antibiotic resistance quickly by rejigging pumps
Bacteria can rapidly evolve resistance to antibiotics by adapting special pumps to flush them out of their cells, according to new research from the Quadram Institute and University of East Anglia.
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Eye drops cause infection long before CDC warning
A patient was diagnosed with a dangerous Pseudomonas aeruginosa eye infection caused by contaminated eye drops, months before the CDC issued warnings against using the product.
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Tobacco plant engineered to act as drug factory
Researchers have engineered a close relative of tobacco, Nicotiana benthamiana, to churn out peptides with antibiotic activity against some of the nastiest pathogens known to medicine.
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Warning as entire ICU contaminated with superbug
Researchers have called for urgent measures to protect hospitals after an entire ICU was contaminated with an outbreak of antibiotic-resistant bacteria.