All Antimicrobial Resistance articles – Page 20
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Genetic sequencing uncovers unexpected source of pathogens in floodwaters
Local rivers and streams were the source of the Salmonella enterica contamination along coastal North Carolina after Hurricane Florence in 2018 – not the previously suspected high number of pig farms in the region.
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Nanoparticles with antibacterial action shorten duration of tuberculosis treatment
A low-cost technology involving nanoparticles loaded with antibiotics and other antimicrobial compounds that can be used in multiple attacks on infections by the bacterium responsible for most cases of tuberculosis has been developed.
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AMR leads to more deaths and illnesses in the WHO African region than anywhere else
More than 1.05 million deaths were associated with antimicrobial resistance (AMR) and 250,000 deaths were attributable to AMR in the WHO African region, posing an unprecedented health threat.
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New weapon against the super tough C diff bacteria shows promise
A researcher has demonstrated that a newer generation tetracycline antibiotic, Omadacycline, may be a promising tool in combating the resilient bacteria Clostridioides difficile (C diff), which causes an infection often picked up in hospitals.
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Careers
A day in the life of a microbiology technician
A glimpse into the world of Bactobio with Grace Cox and Shinjini Mathur who are unleashing the power of microbes to produce novel antimicrobials - from culturing novel strains to harnessing their potential for global health solutions.
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Photodynamic action weakens resistance to antibiotics in bacteria that attack airways
A study of photodynamic inactivation (PDI) showed it has a novel capacity to modify bacterial sensitivity to antibiotics according to dosage, reducing the resistance and persistence of both standard and clinical strains.
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Researchers discover how to sabotage antibiotic-resistant ‘superbugs’
Scientists say they have learned how to sabotage a key piece of machinery that pathogens use to infect their host cells, and have developed a test to identify the next-generation drugs to target this vulnerable cellular machinery.
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Researchers outline AI blueprint to help tackle antimicrobial resistance on a global scale
Researchers from the University of Liverpool have outlined a framework for artificial intelligence (AI) to improve antimicrobial use and infection care, helping to address the global challenge of antimicrobial resistance (AMR).
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Team-up of two new substances paves the way for new antibiotics
A new study shows how a combination of two new substances effectively kills methicillin-resistant Staphylococcus aureus (MRSA).
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Microbiome insights found in faeces help predict infections in liver transplant patients
In a new study, researchers at the University of Chicago were able to predict postoperative infections in liver transplant patients by analyzing molecules in their poop. Their analysis represents a key leap forward in exploring the connection between the gut microbiome — the bacteria that inhabit the human body — ...
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Diverse gut bacteria communities protect against harmful pathogens by nutrient blocking
A new study demonstrates that diverse communities of resident bacteria can protect the human gut from disease-causing microorganisms. However, this protective effect is lost when only single species of gut bacteria are present.
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Cockroaches can transmit antimicrobial resistance genes between groups
A new paper describes a study of antimicrobial resistance (AMR) transmission among cockroaches, with implications for AMR transmission in humans.
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Dr Thomas Thompson named as winner of inaugural John Snow Prize
Dr Thomas Thompson of Queen’s University Belfast in Northern Ireland has been named as this year’s winner of the inaugural John Snow Prize for microbiology. The prize is part of the Applied Microbiology International Horizon Awards, which celebrate the brightest minds in the field and promote the ...
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Researchers develop potential vaccine against antibiotic-resistant enterococci
Researchers have discovered how to create an enterococcal vaccine that is relatively easy to produce and takes advantage of membrane vesicles.
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Novel compounds promise success in the fight against tuberculosis and depression
Scientists have shown that a specific polyprenylated polycyclic acylphloroglucinol, PPAP53, is able to activate human macrophages to fight resistant tuberculosis bacteria without being toxic to the macrophages themselves.
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New study considers risks of colistin and carbapenem resistance posed by aquatic farms
Aquatic farms could serve as a potential reservoir of colistin and carbapenem resistance, a new study warns. The review, by researchers at the University of Manchester, ‘An Update on the Prevalence of Colistin and Carbapenem-Resistant Gram-Negative Bacteria in Aquaculture: an Emerging Threat to Public Health’, has been accepted by the ...
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Ice core proposal could revolutionise antibiotic discovery
A perspective article outlines a revolutionary approach to antibiotic discovery using ice cores, at a time when antimicrobial resistance (AMR) is projected to cause 10 million deaths per year by 2050.
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Drug-resistant tuberculosis may be under-diagnosed, reveals genomic analysis
This genomic sequencing study, in southern Mozambique, is the first to characterise the drug resistance profile at the population level and identify mutations that escape routine diagnostic tests.
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Blood glycerol levels linked to tuberculosis severity in Type 2 Diabetes
A study has uncovered that elevated glycerol levels are responsible for increased severity of tuberculosis (TB) disease in experimental models with Type 2 diabetes (T2D).
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Researchers develop material that reduces bacterial infection and speeds up bone healing
Researchers have developed a new surgical implant that has the potential to transform the treatment of complex bone infections.