All Antimicrobial Resistance articles
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Potentially harmful bacteria slip through antimicrobial showerheads
Researchers report that antimicrobial silver-containing showerheads are no ’silver bullet’. In real-world showering conditions, most microbes aren’t exposed to the silver long enough to be killed.
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New discovery provides hope in fighting drug-resistant malaria
Researchers have described how they may have found a new target in Plasmodium falciparum, the deadliest malaria parasite: a cholesterol-managing protein called PfNCR1.
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Scientists find a vulnerability in antibiotic resistance mechanism
Superbugs, bacteria that are immune to multiple antibiotics, pose a great challenge to modern medicine. Researchers from the B CUBE - Center for Molecular Bioengineering at TUD Dresden University of Technology and Institut Pasteur in Paris identified a weakness in the bacterial machinery that drives antibiotic resistance adaptation. Their findings, ...
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Breakthrough infection test designed to tackle AMR on target for 2025 UK NHS availability after positive trial results
UK medtech company Presymptom Health has announced positive results from its clinical trial of diagnostic technology in the management of infection and sepsis in patients presenting to Emergency Departments with respiratory infection.
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Staphylococcus aureus thwarts vaccines by turning on a protein that halts immune response
Approximately 30 clinical trials to date have failed to result in an effective human vaccine for Staphylococcus aureus but researchers have now identified a key reason for these failures, indicating that it may be possible to modify the vaccines to work in humans.
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Deadly mould strains highly likely to acquire resistance to new drugs
Scientists have identified strains of one of the world’s most dangerous fungal pathogens, already resistant to our most effective antifungal drugs, which are also five times more likely to acquire resistance to desperately needed new treatments in development. Source: Ufficio Comunicazione, Azienda Ospedaliera SS. Antonio e ...
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From Yemen to Mayotte, the spread of a highly drug-resistant cholera strain
Scientists have revealed the spread of a highly drug-resistant cholera strain. The strain is resistant to ten antibiotics – including azithromycin and ciprofloxacin, two of the three recommended for treating cholera – and was identified for the first time in Yemen in 2018-2019.
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Scientists collect ‘microbial fingerprints’ found in household plumbing
Scientists sampled faucets in eight homes for seven days to see the flow and change of different bacteria populations. They found that, though houses generally shared major categories of bacteria, down to the species level, there was wide variation from house to house.
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Urgent need for integrated detection strategies for AMR in water environments
A new review calls attention to the urgent need for integrated detection strategies that combine the precision of molecular tools with the cost-effectiveness of traditional methods which could enable more efficient, accessible, and scalable AMR monitoring.
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A new class of antivirals could help prevent future pandemics
A new study introduces a proof-of-concept for a novel class of antivirals that would target a type of enzyme essential not just to SARS, but also many RNA viruses, including Ebola and dengue, as well as cytosolic-replicating DNA viruses, including Pox viruses.
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A team of scientists join forces for the fight against deadly childhood disease
A global consortium of scientists has been tasked with better understanding the scale of Shigella infections and the role of antibiotic resistance in seven countries.
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New study highlights rise in severe Shigella infections among homeless patients in Vancouver
A recent study has uncovered an increase in severe multidrug-resistant (MDR) Shigella sonnei infections, particularly among people experiencing homelessness (PEH) in Vancouver, Canada.
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Cold plasma isn’t just for sterilisation - it could become a vital green tool in water purification
Cold plasma isn’t just for sterilisation, but offers potential as a sustainable water treatment that can target stubborn contaminants like biofilms and pharmaceuticals, according to a new review.
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Bacteria ditch tags to dodge antibiotics
Bacteria modify their ribosomes when exposed to widely used antibiotics, according to new research. The subtle changes might be enough to alter the binding site of drug targets and constitute a possible new mechanism of antibiotic resistance.
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Pandrug-resistant bacteria from the war in Ukraine are extremely pathogenic
Using samples from 141 war-wounded it was shown that several bacteria types were resistant to broad-spectrum antibiotics and that six per cent of samples were resistant to all antibiotics that the researchers tested.
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Antibiotics initiated for suspected community-acquired pneumonia even when chest radiography results are negative
A new study shows that many general practitioners prescribe antibiotics for suspected community-acquired pneumonia even when chest X-ray results are negative, highlighting a gap between guidelines and actual practice.
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Scientists uncover new mechanism in bacterial DNA enzyme opening pathways for antibiotic development
Researchers have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic target. This enzyme, present in bacteria but absent in humans, plays a crucial role in supercoiling DNA, a necessary process for bacterial survival.
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Artificial intelligence can be used to treat infections more accurately
New research has shown that using artificial intelligence (AI) can improve how we treat urinary tract infections (UTIs), and help to address antimicrobial resistance (AMR).
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Genomic surveillance studies reveal circulation of multidrug-resistant Enterobacterales in Europe
Two studies indicate warning signs about spread of bacteria resistant to the same group of antibiotics (carbapenems) in both healthcare and community settings across Europe.
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Researchers catalog the microbiome of US rivers
River microbes found near wastewater treatment plants expressed high levels of antibiotic resistance genes, reveals a study of the presence and function of microbes in rivers covering 90% of the watersheds in the continental U.S.