All Antibiotics articles – Page 5
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Antibiotic pollution disrupts the gut microbiome and blocks memory in aquatic snails
Antibiotics prevent snails from forming new memories by disrupting their gut microbiome, a new study reveals, highlighting the damaging effects that human pollution could be having on aquatic wildlife.
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The effect of combinations of antibiotics and natural products on antimicrobial resistance
Thymol, rosemary oil, curcumin, capsicum, and moringa seed extract showed the highest synergistic activity with tested antibiotics against two key pathogens, a new study shows.
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New antibiotic kills pathogenic bacteria, but spares healthy gut microbes
Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut.
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Scientists develop novel methods to detect antibiotics in vegetables and earthworms
Using highly sensitive analytical methods, a research team has managed to detect very low levels of antimicrobials in vegetables and earthworms.
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Antibiotic ‘Velcro’ gives bacteria a sticky situation
A small antibiotic called plectasin uses an innovative mechanism to kill bacteria. By assembling into large structures, plectasin latches onto its target on the bacterial cell surface - scientists have now mapped how this bond is formed.
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New small molecule found to suppress the evolution of antibiotic resistance in bacteria
Researchers have developed a new small molecule that can suppress the evolution of antibiotic resistance in bacteria and make resistant bacteria more susceptible to antibiotics.
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Call issued for actionable steps in response to the rising threat of antimicrobial resistance (AMR)
The AMR Multi-Stakeholder Partnership Platform has developed key recommendations for action on antimicrobial resistance for consideration by United Nations (UN) Member States in the UN General Assembly High-Level Meeting on AMR.
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Researchers may have come up with second chance for antibiotic agent
A new study focuses on the protein peptide deformylase (PDF), which is involved in protein maturation processes in bacterial cells. While the original drug candidate had to be discarded, modification of the molecule could offer a second chance.
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Scientists uncover mechanism that could weaken virulence of Pseudomonas aeruginosa
Researchers have found a mechanism that makes it possible to weaken the virulence of opportunistic bacterial pathogen Pseudomonas aeruginosa - based on this knowledge, a new approach for antibiotics can be developed.
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Commonly used antibiotic brings more complications, death in the sickest patients
Treatment with the commonly used antibiotic piperacillin/tazobactam was associated with a 5 percent increase in 90-day mortality, more days on a ventilator, and more time with organ failure for patients with sepsis, a new study finds.
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Astragalus polysaccharide enhances voriconazole metabolism under inflammatory conditions through the gut microbiota
Astragalus polysaccharide alleviates the reduction of VRC metabolism induced by LPS by inhibiting lipid accumulation and inflammatory cytokine levels in the serum and liver and improving the metabolic function of the liver, a new study shows.
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Scientists warn of overuse of antibiotics in newborns with suspected sepsis
Newborns in Sweden are given antibiotics for suspected sepsis to an unjustified extent, reveals a study of more than one million newborns. Despite a significant reduction in sepsis rate in the group, the use of antibiotics has not decreased.
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Study finds resistance to critically important antibiotics in uncooked meat sold for human and animal consumption
New research has found substantial levels of resistance to critically important antibiotics in meat sold for human and animal consumption.
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Treatment for deadly superbug C. diff may be weakening
The antibiotic vancomycin, recommended as first-line treatment for infection caused by the deadly superbug C. difficile (C. diff), may not be living up to its promise, according to new research.
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Cocktails of antibiotics, probiotics and prebiotics hold promise in treating a common form of irritable bowel syndrome
Personalised “cocktails” of antibiotics, probiotics and prebiotics hold great promise in the treatment of a common form of irritable bowel syndrome (IBS), a new study suggests.
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Antibiotic use in patients hospitalised with COVID-19 appears to have no beneficial effect on clinical outcomes
An analysis of more than 1,300 German adults hospitalised with moderate COVID-19 finds treatment with antibiotics was associated with five times greater likelihood of COVID-19 deterioration compared to patients not given antibiotics.
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Major genetic meta-analysis reveals how antibiotic resistance in babies varies according to mode of birth, prematurity, and where they live
Meta-analysis of genetic studies from 10 countries finds infants born by C-section have more antibiotic resistance genes; antibiotic use and prematurity also fuel resistance.
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Rise seen in use of antibiotics for conditions they can’t treat – including COVID-19
A five-year trend study shows a rebound in inappropriate use after an early-pandemic dip, and a need to tackle overuse in all patients during viral illness outbreaks.
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Antibiotics aren’t effective for most lower tract respiratory infections
Use of antibiotics provided no measurable impact on the severity or duration of coughs even if a bacterial infection was present, finds a large, prospective study of people who sought treatment for lower-respiratory tract infections.
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Membrane-piercing drugs bring multidrug-resistant pathogens to their knees
A research team has introduced a method for the development of novel antibiotics to fight resistant pathogens. The drugs are based on protein building blocks with fluorous lipid chains.