All Antibiotics articles – Page 4
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AI opens door to safe, effective new antibiotics to combat resistant bacteria
A large language model—an AI tool like the one that powers ChatGPT—has been used to engineer a version of a bacteria-killing drug that was previously toxic in humans.
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Derivative of the long pepper battles bacterial biofilms
Scientists investigating the long pepper - known in traditional medicine for its treatment of a variety of illnesses - have created a derivative that disrupts bacterial chemical communication.
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Surgical Infection Society issues new guidelines on the management of intra-abdominal infection
The Surgical Infection Society (SIS) has presented new evidence-based guidelines for the management of intra-abdominal infection (IAI) in the peer-reviewed journal Surgical Infections. “These guidelines are critical in the ongoing work by the Surgical Infection Society to decrease the number of deaths from the most common ...
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Small animals acquire genes from bacteria that can produce antibiotics
A group of small, freshwater animals protect themselves from infections using antibiotic recipes “stolen” from bacteria, according to new research.
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E. coli variant may cause antimicrobial resistance in dogs and humans
Researchers studying antimicrobial-resistant E. coli – the leading cause of human death due to antimicrobial resistance worldwide – have identified a mechanism in dogs that may render multiple antibiotic classes ineffective.
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Early life antibiotic increases risk of asthma: providing clues to a potential prevention adult asthma
Early exposure to antibiotics can trigger long term susceptibility to asthma, according to researchers who isolated a molecule produced by gut bacteria that in the future could potentially be trialed as a dietary supplement for children at risk of asthma.
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Scientists discover new defense mechanism in bacteria
Researchers investigated a bacterial defence mechanism that uses cell-to-cell communication to ‘warn’ unaffected bacteria, which can then anticipate, shield themselves and spread the warning signal.
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Western superbugs do not dominate in Pakistan, study reveals
Certain antibiotic-resistant strains of bacteria endemic to the UK, Norway and the USA have not taken hold in Pakistan despite the widespread use of antibiotics in this region.
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AI helps mine genetic elements from ancient genomes to tackle antibiotic resistance
Scientists have developed an artificial intelligence tool to mine the vast and largely unexplored biological data—more than 10 million molecules of both modern and extinct organisms— to discover new candidates for antibiotics.
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Researchers unlock gateway to open up more bacterial species for research
Researchers have introduced a novel approach that can make many more bacteria amenable to genetic engineering. Their method, called IMPRINT, uses cell-free systems to enhance DNA transformation across various bacterial strains.
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Scientists can now detect antibiotics in your fingerprints – aiding the fight against drug-resistant TB
A fingerprint may soon be all a doctor needs to check whether tuberculosis patients are taking their antibiotics – thanks to a new study. Scientists successfully detected the drugs in finger sweat – and with almost the same accuracy as a blood test.
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E. coli sends out SOS when antibiotics attack, sparking emergency mode
Antibiotics damage E. coli DNA, including by causing formation of single strands of incomplete DNA inside the cell. When that happens, it’s like lighting a match under a smoke detector, according to a new study.
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Temperature could be the new weapon in the battle against antibiotic resistance
Scientists have found that a small increase in temperature from 37 to 40 degrees Celsius drastically changes the mutation frequency in E. coli bacteria, which facilitates the development of resistance.
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AI enables faster, more effective antibiotic treatment of sepsis
Sepsis is a life-threatening infection complication and accounts for 1.7 million hospitalizations and 350,000 deaths annually in the U.S. Fast and accurate diagnosis is critical, as mortality risk increases up to 8% every hour without effective treatment. Source: Ilanaer42 However, the current diagnostic standard is reliant on ...
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Upper surface of coastal waters can accumulate bacteria and antibiotics
Antibiotics in the uppermost water surface, known as the sea surface microlayer, can significantly affect the number of bacteria present and contribute to the adaptation of marine bacteria against widely used antibiotics. In new research presented at ASM Microbe, scientists directly assessed the potential effects of antibiotics ...
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Liposomes can target antibiotics right to where they’re needed in wounds
The antibiotic gentamicin can be encapsulated into liposomes, allowing for more accurate use in situations such as wound treatment, according to new research presented at the recent Letters in Applied Microbiology ECS Research Symposium.
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Largest-ever antibiotic discovery effort uses AI to uncover potential cures in microbial dark matter
Researchers used machine learning to search for antibiotics in a vast dataset containing the recorded genomes of tens of thousands of bacteria and other primitive organisms, yielding nearly one million potential antibiotic compounds.
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Bone loss drugs can help azoles fight fungal infections
A new study suggests that adding common bone loss drugs to azoles can improve efficacy. In lab tests, combinations of these drugs worked against dermatophyte species and prevented resistance.
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Anti-inflammatory curbs spread of fungi causing serious blood infections
Researchers have discovered that a common anti-inflammatory drug, mesalamine, can replace the work of good bacteria in fighting the fungus Candida albicans in the gut.
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Novel triple antibiotic combination offers breakthrough in combatting antibiotic resistance
A new study unveils a promising triple combination of antibiotics that significantly expands our arsenal against drug-resistant bacteria.