All Antibiotics articles – Page 3
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Swedish research on antibiotic pollution becomes UN declaration after 17 years
In 2007, researchers at the University of Gothenburg, Sweden published the first in a series of studies showing massive pollution with antibiotics from pharmaceutical factories in India. In connection with the ongoing UN General Assembly in New York, a declaration was approved that underlines the risks and calls for measures ...
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World leaders commit to decisive action on antimicrobial resistance
Global leaders have approved a political declaration at the 79th United Nations General Assembly (UNGA) High-Level Meeting on Antimicrobial Resistance (AMR), pledging to cut the estimated 4.95 million human deaths associated with bacterial AMR annually by 10% by 2030.
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European capacity for antibiotic R&D requires long-term funding
The AMR Accelerator projects have called for long-term investments, stressing the need to preserve the European capacity for antibiotic R&D by sustaining the assets, expertise, and research infrastructures required to develop new treatments for drug-resistant infections.
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Study reveals link between microbiome and aggression
A new study has unveiled significant evidence connecting the gut microbiome to aggressive behavior in mice. The research explores how disruptions in the microbiome, particularly due to antibiotic use in early life, can lead to increased aggression.
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Fleming Initiative raises first £100m in the global fight against AMR
Three new partners have pledged additional funding and resources to the Fleming Initiative’s global effort to combat antimicrobial resistance (AMR), as leading medical expert Professor Lord Ara Darzi calls for tighter restrictions on the use of antibiotics.
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Scientists team up to create synthetic process for antibiotic drug discovery
Researchers will team up to explore and develop a novel platform or chemical process for synthesizing antibiotic compounds, thanks to a $125,000 grant.
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Antibiotic usage can damage the protective mucus layer in the gut
Researchers have found that a history of repeated antibiotic use causes defects in the normally protective mucus barrier of the gut, due to antibiotic-driven alterations in the microbiota.
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Landmark study reveals how antibiotics contribute to inflammatory bowel disease risk
Researchers have uncovered crucial insights into how antibiotic use increases the risk of inflammatory bowel disease (IBD), demonstrating that antibiotics interfere with the protective mucus layer in the intestine.
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First narrow-spectrum antibiotic successfully eliminates Fusobacterium nucleatum in breakthrough study
Scientists found that FP 100 (Hygromycin A), a first-in-class, small molecule, narrow-spectrum antibiotic, successfully eradicates Fusobacterium nucleatum without harming the oral or gut microbiomes.
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New global guidance aims to curb antibiotic pollution from manufacturing
The World Health Organization (WHO) has published its first-ever guidance on antibiotic pollution from manufacturing, focusing on wastewater and solid waste management.
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Waging war on ‘superbugs’ in aged care
A new study explores the link between the widespread use of antibiotics in residential aged care and the resulting antibiotic resistant bacteria in the gut that can be passed on to other residents
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Scientists discover superbug’s rapid path to antibiotic resistance
Researchers have discovered how a hospital superbug Clostridioides difficile (C.diff) can rapidly evolve resistance to vancomycin. In less than two months the bacteria could develop resistance to 32 times the initial antibiotic concentration.
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Promising antibiotic candidates discovered in microbes deep in the Arctic Sea
A new study demonstrates that prospecting novel habitats like the Arctic Sea can yield novel antivirulence drugs that are less likely to select for resistance.
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Bacteria able to overcome cost of vancomycin resistance in lab setting
Staphylococcus aureus has the potential to develop durable vancomycin resistance, according to a new study.
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C-section antibiotics impact the infant microbiome far less than infant diet
A study has confirmed that although prophylactic antibiotics given ahead of a Caesarian section can cause subtle changes to the infant microbiome, they are much less significant than the impact of how the babies are fed.
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New evidence for a connection between antibiotic use and autoimmune diseases
A new connection has been revealed between depletion of gut bacteria caused by antibiotics and development of autoimmune diseases. Clearance of dead cells involves not only local signals from within a tissue but also distant signals from other parts of the body.
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Hospital awarded $12m to study best approach to treat mild pneumonia in young children
Ann & Robert H. Lurie Children’s Hospital of Chicago, in partnership with University of Utah Health, has been approved for $12 million in research funding for a study that will compare two ways to use antibiotics in young children with mild pneumonia.
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Bacterial gut diversity improves the athletic performance of racehorses
The composition of gut bacteria of thoroughbred racehorses at one-month-old can predict their future athletic performance, according to a new study.
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Researchers discover source of deadly fungal infections in bone marrow transplant patients
Scientists have found that heteroresistance is the reason a small number of transplant patients developed bloodstream infections, despite receiving prophylaxis with the antifungal drug micafungin.
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Scientists solve mystery of bacterial scavenging machinery
Scientists investigated how the oleate shuttle from FakB2 to FakA kinase works in the Fak system, which is exploited by the zoonotic pathogen Streptococcus suis (S. suis) pathogen to scavenge exogenous fatty acid (eFA).