All Antibiotics articles – Page 3
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E. coli sends out SOS when antibiotics attack, sparking emergency mode
Antibiotics damage E. coli DNA, including by causing formation of single strands of incomplete DNA inside the cell. When that happens, it’s like lighting a match under a smoke detector, according to a new study.
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Temperature could be the new weapon in the battle against antibiotic resistance
Scientists have found that a small increase in temperature from 37 to 40 degrees Celsius drastically changes the mutation frequency in E. coli bacteria, which facilitates the development of resistance.
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AI enables faster, more effective antibiotic treatment of sepsis
Sepsis is a life-threatening infection complication and accounts for 1.7 million hospitalizations and 350,000 deaths annually in the U.S. Fast and accurate diagnosis is critical, as mortality risk increases up to 8% every hour without effective treatment. Source: Ilanaer42 However, the current diagnostic standard is reliant on ...
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Upper surface of coastal waters can accumulate bacteria and antibiotics
Antibiotics in the uppermost water surface, known as the sea surface microlayer, can significantly affect the number of bacteria present and contribute to the adaptation of marine bacteria against widely used antibiotics. In new research presented at ASM Microbe, scientists directly assessed the potential effects of antibiotics ...
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Liposomes can target antibiotics right to where they’re needed in wounds
The antibiotic gentamicin can be encapsulated into liposomes, allowing for more accurate use in situations such as wound treatment, according to new research presented at the recent Letters in Applied Microbiology ECS Research Symposium.
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Largest-ever antibiotic discovery effort uses AI to uncover potential cures in microbial dark matter
Researchers used machine learning to search for antibiotics in a vast dataset containing the recorded genomes of tens of thousands of bacteria and other primitive organisms, yielding nearly one million potential antibiotic compounds.
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Bone loss drugs can help azoles fight fungal infections
A new study suggests that adding common bone loss drugs to azoles can improve efficacy. In lab tests, combinations of these drugs worked against dermatophyte species and prevented resistance.
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Anti-inflammatory curbs spread of fungi causing serious blood infections
Researchers have discovered that a common anti-inflammatory drug, mesalamine, can replace the work of good bacteria in fighting the fungus Candida albicans in the gut.
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Novel triple antibiotic combination offers breakthrough in combatting antibiotic resistance
A new study unveils a promising triple combination of antibiotics that significantly expands our arsenal against drug-resistant bacteria.
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Antibiotic pollution disrupts the gut microbiome and blocks memory in aquatic snails
Antibiotics prevent snails from forming new memories by disrupting their gut microbiome, a new study reveals, highlighting the damaging effects that human pollution could be having on aquatic wildlife.
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The effect of combinations of antibiotics and natural products on antimicrobial resistance
Thymol, rosemary oil, curcumin, capsicum, and moringa seed extract showed the highest synergistic activity with tested antibiotics against two key pathogens, a new study shows.
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New antibiotic kills pathogenic bacteria, but spares healthy gut microbes
Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut.
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Scientists develop novel methods to detect antibiotics in vegetables and earthworms
Using highly sensitive analytical methods, a research team has managed to detect very low levels of antimicrobials in vegetables and earthworms.
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Antibiotic ‘Velcro’ gives bacteria a sticky situation
A small antibiotic called plectasin uses an innovative mechanism to kill bacteria. By assembling into large structures, plectasin latches onto its target on the bacterial cell surface - scientists have now mapped how this bond is formed.
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New small molecule found to suppress the evolution of antibiotic resistance in bacteria
Researchers have developed a new small molecule that can suppress the evolution of antibiotic resistance in bacteria and make resistant bacteria more susceptible to antibiotics.
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Call issued for actionable steps in response to the rising threat of antimicrobial resistance (AMR)
The AMR Multi-Stakeholder Partnership Platform has developed key recommendations for action on antimicrobial resistance for consideration by United Nations (UN) Member States in the UN General Assembly High-Level Meeting on AMR.
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Researchers may have come up with second chance for antibiotic agent
A new study focuses on the protein peptide deformylase (PDF), which is involved in protein maturation processes in bacterial cells. While the original drug candidate had to be discarded, modification of the molecule could offer a second chance.
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Scientists uncover mechanism that could weaken virulence of Pseudomonas aeruginosa
Researchers have found a mechanism that makes it possible to weaken the virulence of opportunistic bacterial pathogen Pseudomonas aeruginosa - based on this knowledge, a new approach for antibiotics can be developed.
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Commonly used antibiotic brings more complications, death in the sickest patients
Treatment with the commonly used antibiotic piperacillin/tazobactam was associated with a 5 percent increase in 90-day mortality, more days on a ventilator, and more time with organ failure for patients with sepsis, a new study finds.
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Astragalus polysaccharide enhances voriconazole metabolism under inflammatory conditions through the gut microbiota
Astragalus polysaccharide alleviates the reduction of VRC metabolism induced by LPS by inhibiting lipid accumulation and inflammatory cytokine levels in the serum and liver and improving the metabolic function of the liver, a new study shows.