All Antibiotics articles – Page 2
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Scientists discover superbug’s rapid path to antibiotic resistance
Researchers have discovered how a hospital superbug Clostridioides difficile (C.diff) can rapidly evolve resistance to vancomycin. In less than two months the bacteria could develop resistance to 32 times the initial antibiotic concentration.
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Promising antibiotic candidates discovered in microbes deep in the Arctic Sea
A new study demonstrates that prospecting novel habitats like the Arctic Sea can yield novel antivirulence drugs that are less likely to select for resistance.
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Bacteria able to overcome cost of vancomycin resistance in lab setting
Staphylococcus aureus has the potential to develop durable vancomycin resistance, according to a new study.
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C-section antibiotics impact the infant microbiome far less than infant diet
A study has confirmed that although prophylactic antibiotics given ahead of a Caesarian section can cause subtle changes to the infant microbiome, they are much less significant than the impact of how the babies are fed.
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New evidence for a connection between antibiotic use and autoimmune diseases
A new connection has been revealed between depletion of gut bacteria caused by antibiotics and development of autoimmune diseases. Clearance of dead cells involves not only local signals from within a tissue but also distant signals from other parts of the body.
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Hospital awarded $12m to study best approach to treat mild pneumonia in young children
Ann & Robert H. Lurie Children’s Hospital of Chicago, in partnership with University of Utah Health, has been approved for $12 million in research funding for a study that will compare two ways to use antibiotics in young children with mild pneumonia.
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Bacterial gut diversity improves the athletic performance of racehorses
The composition of gut bacteria of thoroughbred racehorses at one-month-old can predict their future athletic performance, according to a new study.
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Researchers discover source of deadly fungal infections in bone marrow transplant patients
Scientists have found that heteroresistance is the reason a small number of transplant patients developed bloodstream infections, despite receiving prophylaxis with the antifungal drug micafungin.
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Scientists solve mystery of bacterial scavenging machinery
Scientists investigated how the oleate shuttle from FakB2 to FakA kinase works in the Fak system, which is exploited by the zoonotic pathogen Streptococcus suis (S. suis) pathogen to scavenge exogenous fatty acid (eFA).
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AI opens door to safe, effective new antibiotics to combat resistant bacteria
A large language model—an AI tool like the one that powers ChatGPT—has been used to engineer a version of a bacteria-killing drug that was previously toxic in humans.
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Derivative of the long pepper battles bacterial biofilms
Scientists investigating the long pepper - known in traditional medicine for its treatment of a variety of illnesses - have created a derivative that disrupts bacterial chemical communication.
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Surgical Infection Society issues new guidelines on the management of intra-abdominal infection
The Surgical Infection Society (SIS) has presented new evidence-based guidelines for the management of intra-abdominal infection (IAI) in the peer-reviewed journal Surgical Infections. “These guidelines are critical in the ongoing work by the Surgical Infection Society to decrease the number of deaths from the most common ...
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Small animals acquire genes from bacteria that can produce antibiotics
A group of small, freshwater animals protect themselves from infections using antibiotic recipes “stolen” from bacteria, according to new research.
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E. coli variant may cause antimicrobial resistance in dogs and humans
Researchers studying antimicrobial-resistant E. coli – the leading cause of human death due to antimicrobial resistance worldwide – have identified a mechanism in dogs that may render multiple antibiotic classes ineffective.
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Early life antibiotic increases risk of asthma: providing clues to a potential prevention adult asthma
Early exposure to antibiotics can trigger long term susceptibility to asthma, according to researchers who isolated a molecule produced by gut bacteria that in the future could potentially be trialed as a dietary supplement for children at risk of asthma.
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Scientists discover new defense mechanism in bacteria
Researchers investigated a bacterial defence mechanism that uses cell-to-cell communication to ‘warn’ unaffected bacteria, which can then anticipate, shield themselves and spread the warning signal.
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Western superbugs do not dominate in Pakistan, study reveals
Certain antibiotic-resistant strains of bacteria endemic to the UK, Norway and the USA have not taken hold in Pakistan despite the widespread use of antibiotics in this region.
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AI helps mine genetic elements from ancient genomes to tackle antibiotic resistance
Scientists have developed an artificial intelligence tool to mine the vast and largely unexplored biological data—more than 10 million molecules of both modern and extinct organisms— to discover new candidates for antibiotics.
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Researchers unlock gateway to open up more bacterial species for research
Researchers have introduced a novel approach that can make many more bacteria amenable to genetic engineering. Their method, called IMPRINT, uses cell-free systems to enhance DNA transformation across various bacterial strains.
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Scientists can now detect antibiotics in your fingerprints – aiding the fight against drug-resistant TB
A fingerprint may soon be all a doctor needs to check whether tuberculosis patients are taking their antibiotics – thanks to a new study. Scientists successfully detected the drugs in finger sweat – and with almost the same accuracy as a blood test.