All Antibiotics articles
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News
Scientists uncover how bacterial resistance to synergistic drug treatments is arising
Scientists investigating the potential of combined and more powerful drug treatments have found that antimicrobial resistance to these is arising via the vitamin B2 synthesis pathway.
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News
Novel antibiotic BTZ-043 also reaches tuberculosis bacteria hiding in dead lung tissue
Researchers have shown that the novel antibiotic BTZ-043 effectively penetrates tubercolous lesions and accumulates there in high concentrations. Consequently, the drug can fight Mtb bacteria even in hard-to-reach areas.
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News
No more antibiotics? Scientists pioneer a safer way to protect cultured meat
A new study explores the use of Random Antimicrobial Peptide Mixtures (RPMs) as a safe and effective alternative to antibiotics in cultured meat production. These synthetic peptide cocktails eliminate bacterial contamination without harming stem cell viability or contributing to antibiotic resistance.
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News
Using population-level characteristics for the surveillance of antimicrobial-resistant gonorrhea
As the antimicrobial-resistant (AMR) gonorrhea poses a major threat to public health, there is an urgent need for expanding the surveillance of its prevalance to control the spread of the pathogen, through monitoring its association with the population density and HIV prevalence in cities.
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Protein shuttling mechanism helps bacteria pump out antibiotics
By a joint-university effort, the mechanism of a bacterial efflux pump complex to remove molecules, including antibiotics, has been determined and the extent of bacterial toxin resistance by the complex has also been evaluated with a cutting-edge device.
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AI accelerates the search for new tuberculosis drug targets
A novel biotechnology was developed to utilize artificial intelligence (AI) as a high-throughput way to identify more effective antimicrobial candidates to treat the multi-drug resistant Mycobacterium tuberculosis and understand their underlying modes of action.
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News
Jumbo phages deploying secret handshakes could usher in new antibiotics
Jumbo phages create a restricted space inside bacteria where they can copy their DNA while surrounded by a protective shield. A new study reveals that the shield works via a set of ’secret handshakes’, allowing only a specific set of useful proteins to pass through.
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News
Persister act: Why antibiotics can fail even against non-resistant bacteria
A new study challenges the concept that persisters are the cause of antibiotic ineffectiveness, demonstrating that standard laboratory tests of antimicrobial clearance produce misleading results, giving a false impression of a small group of particularly resilient persisters.
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News
Asthma and antibiotic use may predict nasal polyp recurrence after endoscopic sinus surgery
A recent study suggests that patients with chronic rhinosinusitis, who had undergone endoscopic sinus surgery, have a higher chance of undergoing revision sinus surgery that removes nasal polyps if they have asthma and are using antibiotics.
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News
Antibiotics of the future are prone to bacterial resistance
Two studies have found that resistance can develop against new antibiotics even before they are widely used, compromising their effectiveness from the start. The studies focused on five critical bacterial species and examined 18 new antibiotics.
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News
Researchers identify genetic ‘fingerprint’ to predict drug resistance in bacteria
To avoid antibiotic overuse and allow precise bacterial infection treatment, particularly against bacteria with multidrug resistance, a diagnostic tool was developed that identifies the pattern of DNA repair deficiencies acting as the bacterial antibiotic resistance ‘fingerprint’.
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Shorter, smarter, safer: Short-course antibiotics can revolutionize healthcare
Researchers suggest that short-course antibiotic treatment could be the next game-changing strategy to treat ventilator-associated pneumonia (VAP) in various economic settings. It provides a cost-effective and practical approach that benefits both patients and the healthcare systems.
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Antibiotic treatment for drug-resistant tuberculosis found to be safe and effective in clinical trial
Two clinical trials were conducted to successfully test an oral antibiotic levofloxacin for the preventive treatment of multidrug-resistant tuberculosis (MDR-TB).
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News
New computer models open door to far more targeted antibiotics
A powerful computer-modelling approach has been developed to give the antibiotics a laser-like precision for targeting specific types of bacteria among specific parts of the human body.
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News
Manure management in China cuts river antibiotic pollution but raises groundwater contamination risks
A study of antibiotic pollution patterns in China’s water systems over the past decade found a 59% decrease in antibiotic pollution in rivers, primarily due to reduced direct manure discharge, but antibiotic leaching into groundwater has increased by 15%.
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News
New research reveals reasons for antibiotic usage in Indian chicken farming
New research exploring antibiotic use in chicken farming in eastern India reveals how poultry companies play a significant role in influencing the way antibiotics are used during food production compared to chicken farmers.
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Opinion
Antimicrobials for an Antimicrobial Resistant World
The fight against AMR will require innovation, collaboration, and a fundamental shift in perspective – but it’s a fight we can win.
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News
Tuberculosis strains resistant to new drugs are transmitted between patients
Researchers have identified 514 Mycobacterium tuberculosis strains that are resistant to TB drugs, including both old and new treatment regimens, in 27 countries across four continents. 28% of these strains were transmitted directly from one patient to another.
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Overcoming resistance: McMaster researchers find new utility for old antibiotics
In a recent study, researchers found that zinc plays a vital role in how some of the world’s most dangerous bacteria resist antibiotics.
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News
Exploring the impact of probiotics on gut microbiota disruption caused by antibiotics
In a new review, eight scientists comprehensively examined the evidence on using probiotics to restore the gut bacterial community during and after antibiotic treatment.