All Antibiotics articles
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Exploring the impact of probiotics on gut microbiota disruption caused by antibiotics
In a new review, eight scientists comprehensively examined the evidence on using probiotics to restore the gut bacterial community during and after antibiotic treatment.
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First full characterization of kidney microbiome unlocks potential to prevent kidney stones
Low levels of bacteria like E. coli and Lactobacillus in our urine come from communities in our kidneys, where they promote or prevent kidney stone formation.
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Careers
Van Hung Vuong Le: my year as a Junior Editor with Letters in Applied Microbiology
One year into our Junior Editor training programme with Letters in Applied Microbiology, Van Hung Vuong Le from the University of Exeter reflects on the experience.
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Antibiotics from bacteria could counter biotic stress in crops, replacing synthetic chemicals
Actinomycetes-derived antibiotics and other metabolites could be deployed to mitigate biotic stress in crops, potentially replacing synthetic chemicals as chemo-control agents against phytopathogens, a new review suggests.
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Using antibiotics alone to treat children with appendicitis is a cost-effective and safe alternative to surgery
An analysis of data from more than 1,000 children with uncomplicated acute appendicitis found an antibiotics-only approach resulted in less pain and fewer days off from school during the first year after the initial hospital visit.
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Antibiotics initiated for suspected community-acquired pneumonia even when chest radiography results are negative
A new study shows that many general practitioners prescribe antibiotics for suspected community-acquired pneumonia even when chest X-ray results are negative, highlighting a gap between guidelines and actual practice.
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Scientists uncover new mechanism in bacterial DNA enzyme opening pathways for antibiotic development
Researchers have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic target. This enzyme, present in bacteria but absent in humans, plays a crucial role in supercoiling DNA, a necessary process for bacterial survival.
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Innovative antibiotic shows promise for drug-resistant bacteria
Researchers have demonstrated a potential antibacterial treatment from a modified darobactin, reporting proof-of-concept animal trials on infections caused by bacteria, including E. coli, that are known to develop drug resistance.
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Careers
‘It’s been an eye-opener’: Thomas Thompson on his year as a Junior Editor
One year into our first Junior Editor training programme with Letters in Applied Microbiology, Dr Thomas Thompson of Queen’s University Belfast tells us how he is getting on.
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Global antibiotic consumption has increased by more than 21 percent since 2016
An analysis of antibiotic sales data from 67 countries from 2016-2023 shows a decrease in consumption in high-income countries countered by an increase in middle-income countries.
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Nanoplastics can impair the effect of antibiotics
Researchers investigating how some of the most common nanoplastics interact with tetracycline found significant accumulation of the antibiotics on the surfaces of the nanoplastic particles.
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Faster measurement of response to antibiotic treatment in sepsis patients using Dimeric HNL
The biomarker human neutrophil lipocalin HNL, which was previously shown to be a useful indicator of bacterial infections, may also in the form of Dimeric HNL be used to effectively monitor the success of antibiotic treatment in sepsis.
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First-of-its-kind national trial exploring potential of antibiotics for lowering c-section rates in women with obesity
A multicenter national clinical trial will study whether antibiotics given at the beginning of labor induction result in a decrease in C-sections. The trial is thought to be the first large-scale study of its kind in the United States.
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Antibiotics and antifungals may slightly affect Parkinson’s risk, study finds
A study has found that people who took multiple courses of penicillin antibiotics had a modestly lower risk of developing Parkinson’s disease, a surprising finding that researchers say highlights the complex relationship between bacteria in the digestive tract and brain health.
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Chemical trick activates antibiotic directly at the pathogen
Scientists have seen promising results after experimenting with a click-to-release approach that deploys a masked form of colistin to the site of an infection so that it is no longer as damaging to the kidneys while maintaining its high antibiotic efficacy.
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Scientists probe mechanics of how bacteria and antibiotics interact down to molecular level
Scientists exploring how combinations of antibiotics can fight resistant bacteria have been awarded an $11.8 million grant for work that could help save the tens of thousands of lives lost yearly to infections that are increasingly plaguing humanity.
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Swedish research on antibiotic pollution becomes UN declaration after 17 years
In 2007, researchers at the University of Gothenburg, Sweden published the first in a series of studies showing massive pollution with antibiotics from pharmaceutical factories in India. In connection with the ongoing UN General Assembly in New York, a declaration was approved that underlines the risks and calls for measures ...
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World leaders commit to decisive action on antimicrobial resistance
Global leaders have approved a political declaration at the 79th United Nations General Assembly (UNGA) High-Level Meeting on Antimicrobial Resistance (AMR), pledging to cut the estimated 4.95 million human deaths associated with bacterial AMR annually by 10% by 2030.
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European capacity for antibiotic R&D requires long-term funding
The AMR Accelerator projects have called for long-term investments, stressing the need to preserve the European capacity for antibiotic R&D by sustaining the assets, expertise, and research infrastructures required to develop new treatments for drug-resistant infections.
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Study reveals link between microbiome and aggression
A new study has unveiled significant evidence connecting the gut microbiome to aggressive behavior in mice. The research explores how disruptions in the microbiome, particularly due to antibiotic use in early life, can lead to increased aggression.