All adeno-associated virus articles
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NewsNovel nanosensing technique offers quality control of viral vectors in gene therapy
Researchers report a novel nanosensing technique to measure viral vector characteristics, measuring the ionic current that flows through a nanopore opening when a voltage differential is applied to a solution containing adeno-associated virus.
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NewsNew, modified CRISPR protein can fit inside virus used for gene therapy
Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells. Hongjian Wang and colleagues at Wuhan University, China, present these findings May 23rd in the ...
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NewsComplement system response to AAV vector gene therapy
Recent clinical trials utilizing high doses of adeno-associated virus (AAV) vectors have highlighted a new challenge to AAV gene transfer – activation of the complement system.
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NewsGene-editing technology eliminates EV-A71 RNA viruses
Scientists have developed a CRISPR-Cas13 therapeutic against EV-A71, the RNA virus that causes hand, foot, and mouth disease.
